Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.43 |
| ▸ | PARP1 | P09874 | 4/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9872575 | 0.85 | LMNA (0.42) | LMNAPOLBGAAMAPTTSHR | |
| SCHEMBL9873593 | 0.79 | DRD2 (0.57) | LMNAPOLBGAAMAPTTSHR | |
| SCHEMBL9874113 | 0.78 | TSHR (0.47) | LMNAPOLBGAAMAPTTSHR | |
| SCHEMBL9872840 | 0.78 | LMNA (0.54) | LMNAPOLBGAAMAPTTSHR | |
| SCHEMBL9872533 | 0.78 | DRD2 (0.49) | LMNAPOLBGAAMAPTTSHR | |
| SCHEMBL322162 | 0.75 | LMNA (0.48) | LMNAPOLBGAAMAPTTSHR | |
| SCHEMBL7315449 | 0.75 | LMNA (0.48) | LMNAPOLBGAAMAPTTSHR | |
| SCHEMBL6032898 | 0.73 | APOBEC3A (0.49) | LMNAPOLBGAAMAPTTSHR | |
| Hydrochloric Acid SCHEMBL7325859 | 0.73 | ADRA2A (0.47) | LMNAPOLBGAAMAPTTSHR | |
| SCHEMBL8762607 | 0.73 | DRD2 (0.57) | SLC18A3PARP1DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4988699-A | Treatment of psychological disorders such as schizophrenia, as antipsychotic agents and hypotensive agents | WARNER-LAMBERT COMPANY (US) | 1991-01-29 | — | — | US | disclosed |