Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.53 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.52 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.46 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MRE11 | P49959 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22959810 | 0.99 | ITGB3 (0.54) | ITGB3ITGA2BSIGMAR1HTR4SIRT2 | |
| SCHEMBL8384876 | 0.94 | SIGMAR1 (0.56) | ITGB3ITGA2BSIGMAR1HTR4SIRT2 | |
| SCHEMBL6605317 | 0.88 | SIGMAR1 (0.51) | ITGB3ITGA2BSIGMAR1ALDH1A1L3MBTL1 | |
| SCHEMBL6620815 | 0.86 | KDM4E (0.58) | SIGMAR1HTR4ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL28379360 | 0.84 | GAA (0.44) | ITGB3ITGA2BSIGMAR1HTR4ALDH1A1 | |
| SCHEMBL12869919 | 0.84 | KDM4E (0.60) | SIGMAR1ALDH1A1KDM4EL3MBTL1NPC1 | |
| SCHEMBL11114519 | 0.84 | HTR4 (0.47) | SIGMAR1HTR4ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL5059161 | 0.81 | EGFR (0.53) | ITGB3ITGA2BSIGMAR1ALDH1A1L3MBTL1 | |
| SCHEMBL6382314 | 0.81 | KDM4E (0.58) | ITGB3ITGA2BSIGMAR1HTR4ALDH1A1 | |
| SCHEMBL25134221 | 0.81 | EGFR (0.50) | ITGB3ITGA2BSIGMAR1ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5053503-A | For joining antibodies and metallic radionuclides | CENTOCOR (US) | 1991-10-01 | — | — | US | disclosed |