Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 2/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 6/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 6/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.34 |
| ▸ | STK10 | O94804 | 1/20 | 0.33 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 3/20 | 0.32 |
| ▸ | HTR2B | P41595 | 3/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9874871 | 0.86 | PDE3B (0.37) | PDE3BPDE3ASTK10SLKHSD11B1 | |
| SCHEMBL9874835 | 0.82 | TP53 (0.43) | PDE3BPDE3ATP53MAPTTHRB | |
| SCHEMBL9872637 | 0.82 | MAPT (0.40) | P2RX7PDE3BPDE3ARXFP1TP53 | |
| SCHEMBL9872713 | 0.76 | CYP3A4 (0.41) | — | |
| SCHEMBL9872038 | 0.73 | NOTUM (0.36) | P2RX7PDE3BPDE3ARXFP1NR1H2 | |
| SCHEMBL9872061 | 0.73 | RAB9A (0.45) | RXFP1MAPTSMN1; SMN2 | |
| SCHEMBL9875005 | 0.71 | MAPT (0.42) | TP53MAPTTHRBSMN1; SMN2 | |
| SCHEMBL9872580 | 0.70 | MAPT (0.43) | HSD11B1MAPT | |
| SCHEMBL31490625 | 0.67 | PTPN1 (0.39) | RXFP1TP53MAPTTHRBSMN1; SMN2 | |
| SCHEMBL339071 | 0.64 | POLB (0.38) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017576-A | Antianxiolytic, hypnotic, anticonvulsant, antiepileptic | RHONE-POULENC SANTE (FR) | 1991-05-21 | — | — | US | disclosed |