Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.36 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.35 |
| ▸ | PSD | A5PKW4 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9872637 | 0.84 | MAPT (0.40) | MAPTALDH1A1CYP3A4 | |
| SCHEMBL9872038 | 0.83 | NOTUM (0.36) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL9872061 | 0.83 | RAB9A (0.45) | MAPTKDM4EALDH1A1CYP3A4 | |
| SCHEMBL9875005 | 0.80 | MAPT (0.42) | MAPTHTTMEN1KMT2AMAPK1 | |
| SCHEMBL9874835 | 0.77 | TP53 (0.43) | MAPTCYP3A4 | |
| SCHEMBL9872713 | 0.75 | CYP3A4 (0.41) | CYP3A4 | |
| SCHEMBL9874871 | 0.73 | PDE3B (0.37) | HSD11B1 | |
| SCHEMBL13017188 | 0.71 | MAPT (0.55) | MAPTHTTMEN1KMT2AMAPK1 | |
| SCHEMBL9873453 | 0.70 | P2RX7 (0.35) | MAPTHSD11B1 | |
| SCHEMBL27915252 | 0.66 | AKR1C3 (0.52) | MAPK1BCHEALDH1A1ABCC8KCNJ11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017576-A | Antianxiolytic, hypnotic, anticonvulsant, antiepileptic | RHONE-POULENC SANTE (FR) | 1991-05-21 | — | — | US | disclosed |