Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9872061 | 0.86 | RAB9A (0.45) | MAPTALDH1A1KDM4ENPC1SMN1; SMN2 | |
| SCHEMBL9872637 | 0.85 | MAPT (0.40) | MAPTALDH1A1THRBTP53 | |
| SCHEMBL9872038 | 0.84 | NOTUM (0.36) | MAPTALDH1A1KDM4ENPC1SMN1; SMN2 | |
| SCHEMBL9872580 | 0.80 | MAPT (0.43) | MAPTALDH1A1KDM4EGAAHTT | |
| SCHEMBL9872713 | 0.79 | CYP3A4 (0.41) | — | |
| SCHEMBL9874835 | 0.78 | TP53 (0.43) | MAPTSMN1; SMN2THRBTP53CYP11B2 | |
| SCHEMBL9874871 | 0.73 | PDE3B (0.37) | — | |
| SCHEMBL9874259 | 0.72 | MAPT (0.46) | MAPTLMNAALDH1A1KDM4ENPC1 | |
| SCHEMBL9873453 | 0.71 | P2RX7 (0.35) | MAPTSMN1; SMN2THRBTP53 | |
| SCHEMBL29640556 | 0.70 | KDM4E (0.68) | MAPTLMNAALDH1A1KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017576-A | Antianxiolytic, hypnotic, anticonvulsant, antiepileptic | RHONE-POULENC SANTE (FR) | 1991-05-21 | — | — | US | disclosed |