Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.40 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9872637 | 0.87 | MAPT (0.40) | TP53MAPTTHRBPDE3BPDE3A | |
| SCHEMBL9872713 | 0.85 | CYP3A4 (0.41) | CYP3A4GRM2GRM3 | |
| SCHEMBL9873453 | 0.82 | P2RX7 (0.35) | TP53MAPTTHRBSMN1; SMN2PDE3B | |
| SCHEMBL9872038 | 0.81 | NOTUM (0.36) | TP53MAPTSMN1; SMN2PDE3BPDE3A | |
| SCHEMBL9872061 | 0.81 | RAB9A (0.45) | MAPTSMN1; SMN2CYP3A4GRM2GRM3 | |
| SCHEMBL9874871 | 0.78 | PDE3B (0.37) | PDE3BPDE3A | |
| SCHEMBL9875005 | 0.78 | MAPT (0.42) | TP53MAPTTHRBSMN1; SMN2CYP11B2 | |
| SCHEMBL340807 | 0.77 | MAPT (0.51) | TP53MAPTTHRBSMN1; SMN2 | |
| SCHEMBL9872580 | 0.77 | MAPT (0.43) | MAPTCYP3A4 | |
| SCHEMBL31490607 | 0.74 | TP53 (0.47) | TP53MAPTTHRBSMN1; SMN2PDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017576-A | Antianxiolytic, hypnotic, anticonvulsant, antiepileptic | RHONE-POULENC SANTE (FR) | 1991-05-21 | — | — | US | disclosed |