Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.38 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9872637 | 0.88 | MAPT (0.40) | ALDH1A1MAPTRXFP1CYP3A4GRM2 | |
| SCHEMBL9872038 | 0.87 | NOTUM (0.36) | RAB9ASMN1; SMN2KDM4ENPC1ALDH1A1 | |
| SCHEMBL9875005 | 0.86 | MAPT (0.42) | RAB9ASMN1; SMN2KDM4ENPC1ALDH1A1 | |
| SCHEMBL9872713 | 0.84 | CYP3A4 (0.41) | CYP3A4GRM2GRM3 | |
| SCHEMBL9872580 | 0.83 | MAPT (0.43) | KDM4EALDH1A1MAPTCYP3A4 | |
| SCHEMBL9874835 | 0.81 | TP53 (0.43) | SMN1; SMN2MAPTCYP3A4GRM2GRM3 | |
| SCHEMBL9873447 | 0.80 | MAPT (0.51) | RAB9ASMN1; SMN2KDM4ENPC1ALDH1A1 | |
| SCHEMBL9874259 | 0.77 | MAPT (0.46) | RAB9ASMN1; SMN2KDM4ENPC1ALDH1A1 | |
| SCHEMBL9874871 | 0.76 | PDE3B (0.37) | — | |
| SCHEMBL9873453 | 0.73 | P2RX7 (0.35) | SMN1; SMN2MAPTRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017576-A | Antianxiolytic, hypnotic, anticonvulsant, antiepileptic | RHONE-POULENC SANTE (FR) | 1991-05-21 | — | — | US | disclosed |