Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.34 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.34 |
| ▸ | GCGR | P47871 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9872637 | 0.88 | MAPT (0.40) | TP53PDE3BPDE3ARXFP1CYP3A4 | |
| SCHEMBL9872061 | 0.87 | RAB9A (0.45) | RXFP1CYP3A4GRM2GRM3KDM4E | |
| SCHEMBL9875005 | 0.84 | MAPT (0.42) | TP53KDM4ENPC1MAPTRAB9A | |
| SCHEMBL9872580 | 0.83 | MAPT (0.43) | CYP3A4KDM4EMAPTMEN1KMT2A | |
| SCHEMBL9874835 | 0.81 | TP53 (0.43) | TP53PDE3BPDE3ACYP3A4GRM2 | |
| SCHEMBL9872713 | 0.79 | CYP3A4 (0.41) | CYP3A4GRM2GRM3 | |
| SCHEMBL9874871 | 0.76 | PDE3B (0.37) | NOTUMPDE3BPDE3A | |
| SCHEMBL9873453 | 0.73 | P2RX7 (0.35) | TP53PDE3BPDE3ARXFP1MAPT | |
| SCHEMBL2446099 | 0.67 | GAA (0.39) | GCGRKDM4EMAPTNR1H2NR1H3 | |
| SCHEMBL28567996 | 0.67 | RXFP1 (0.65) | NOTUMTP53RXFP1DHODHKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017576-A | Antianxiolytic, hypnotic, anticonvulsant, antiepileptic | RHONE-POULENC SANTE (FR) | 1991-05-21 | — | — | US | disclosed |