Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 2/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9874569 | 0.86 | RORC (0.41) | RORCTSHRCTSLCTSBCTSS | |
| SCHEMBL9875839 | 0.78 | RORC (0.40) | RORCTSHRCTSLCTSBCTSS | |
| SCHEMBL9873963 | 0.75 | TSHR (0.36) | TSHRTDP1TP53HTTNPSR1 | |
| SCHEMBL9873858 | 0.74 | RORC (0.42) | RORCTSHRCTSLCTSBCTSS | |
| SCHEMBL4505496 | 0.69 | TDP1 (0.44) | TSHRTDP1TP53HTTNPSR1 | |
| SCHEMBL9874790 | 0.69 | TSHR (0.38) | TSHRTDP1TP53HTTNPSR1 | |
| SCHEMBL18916793 | 0.69 | JMJD6 (0.47) | TSHRNPSR1POLBSMN1; SMN2RAB9A | |
| SCHEMBL9872276 | 0.69 | RORC (0.41) | RORCCTSLCTSBCTSSTDP1 | |
| SCHEMBL3147192 | 0.69 | CTSS (0.48) | TSHRCTSLCTSBCTSSTDP1 | |
| SCHEMBL9874015 | 0.67 | LMNA (0.40) | TSHRTDP1TP53HTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990508-A | Reduced side effects | TOYAMA CHEMICAL CO., LTD. (JP) | 1991-02-05 | — | — | US | disclosed |