Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.33 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9768504 | 0.84 | ALDH1A1 (0.40) | MGLLMAOBALDH1A1KMT2AAR | |
| SCHEMBL9329216 | 0.70 | MAOB (0.50) | MAOB | |
| SCHEMBL9659285 | 0.69 | MEN1 (0.52) | ALDH1A1KMT2AF2 | |
| SCHEMBL1243217 | 0.69 | RAB9A (0.47) | MAOBTSHRALDH1A1KMT2ACYSLTR2 | |
| SCHEMBL9813828 | 0.67 | ALDH1A1 (0.58) | TSHRALDH1A1KMT2AGRM4FFAR1 | |
| SCHEMBL12017500 | 0.67 | LOXL2 (0.38) | ADRB2ALDH1A1 | |
| SCHEMBL10426903 | 0.67 | THRB (0.38) | MGLLKMT2ACYSLTR2CYSLTR1FFAR1 | |
| SCHEMBL9829365 | 0.66 | CYSLTR1 (0.65) | CYSLTR2CYSLTR1FFAR1 | |
| SCHEMBL7446675 | 0.66 | CYP4F2 (0.46) | PPARDNR1H4FFAR1 | |
| SCHEMBL14021849 | 0.66 | RAB9A (0.50) | MAOBLTA4HKMT2ACYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006542-A | Cardiovascular agents | E. R. SQUIBB & SONS, INC. (US) | 1991-04-09 | — | — | US | disclosed |