Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 2/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GRK2 | P25098 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9874447 | 0.84 | MGLL (0.38) | ALDH1A1MAOBKMT2AARMGLL | |
| SCHEMBL9659285 | 0.83 | MEN1 (0.52) | ALDH1A1KMT2APOLB | |
| SCHEMBL9768505 | 0.76 | ADAM17 (0.47) | ALDH1A1MAOBKMT2AGAAMMP1 | |
| SCHEMBL9329216 | 0.73 | MAOB (0.50) | MAOB | |
| SCHEMBL9768486 | 0.72 | PTGIR (0.55) | ALDH1A1GAAMMP1 | |
| SCHEMBL4819394 | 0.72 | SOD1 (0.45) | ALDH1A1KMT2AGAALMNA | |
| SCHEMBL5026313 | 0.72 | IGF1R (0.39) | ALDH1A1MAOBKCNH2 | |
| SCHEMBL9659367 | 0.71 | F2 (0.59) | ALDH1A1KMT2AGAA | |
| SCHEMBL9768512 | 0.71 | MGLL (0.50) | ALDH1A1KMT2AGAALMNAMGLL | |
| SCHEMBL9813770 | 0.69 | PTGIR (0.54) | ALDH1A1GAAMMP1PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5070099-A | THROMBOXANE ANTAGONISTS | E. R. SQUIBB & SONS, INC. (US) | 1991-12-03 | — | — | US | disclosed |
| US-5006542-A | Cardiovascular agents | E. R. SQUIBB & SONS, INC. (US) | 1991-04-09 | — | — | US | disclosed |