Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9874916 | 0.79 | SMN1; SMN2 (0.42) | TDP1KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL9879839 | 0.75 | LMNA (0.41) | TDP1KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL9381137 | 0.73 | GABRP (0.39) | TDP1KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL9873674 | 0.71 | KMT2A (0.42) | KMT2AMEN1LMNACYP1A2CYP2C9 | |
| SCHEMBL9874472 | 0.71 | SMN1; SMN2 (0.37) | KMT2ANPC1RAB9AMEN1CYP1A2 | |
| SCHEMBL9872674 | 0.68 | ALDH1A1 (0.45) | KMT2ANPC1RAB9AMEN1LMNA | |
| SCHEMBL11658582 | 0.64 | SMN1; SMN2 (0.60) | KMT2AMEN1LMNACYP1A2CYP2C9 | |
| SCHEMBL17963199 | 0.64 | ALDH1A1 (0.79) | KMT2ANPC1RAB9AMEN1LMNA | |
| SCHEMBL9874474 | 0.64 | SMN1; SMN2 (0.41) | TDP1KMT2AMEN1LMNAL3MBTL1 | |
| SCHEMBL11654865 | 0.63 | SMN1; SMN2 (0.58) | KMT2AMEN1LMNACYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026711-A | Prevention and treatment of cardiovascular disorders and infections states; anxiolytic and anti-allergic agents | SANOFI (FR) | 1991-06-25 | — | — | US | disclosed |