Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.57 |
| ▸ | DRD3 | P35462 | 5/20 | 0.57 |
| ▸ | DRD4 | P21917 | 4/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9873593 | 0.92 | DRD2 (0.57) | DRD2DRD3DRD4TSHRLMNA | |
| SCHEMBL9872533 | 0.81 | DRD2 (0.49) | DRD2DRD3DRD4TSHRLMNA | |
| SCHEMBL9874903 | 0.78 | SIGMAR1 (0.43) | DRD2DRD3DRD4TSHRLMNA | |
| Ci-1007 SCHEMBL7783725 | 0.73 | DRD2 (1.00) | DRD2DRD3DRD4 | |
| SCHEMBL9874743 | 0.73 | LMNA (0.51) | DRD2DRD3TSHRLMNAPOLB | |
| SCHEMBL9373972 | 0.70 | DRD2 (0.82) | DRD2DRD3DRD4 | |
| SCHEMBL9373964 | 0.70 | DRD2 (0.82) | DRD2DRD3DRD4 | |
| SCHEMBL7803655 | 0.70 | DRD2 (0.67) | DRD2DRD3DRD4ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL7812639 | 0.70 | DRD2 (0.80) | DRD2DRD3DRD4 | |
| Hydrochloric Acid SCHEMBL7812638 | 0.70 | DRD2 (0.80) | DRD2DRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4988699-A | Treatment of psychological disorders such as schizophrenia, as antipsychotic agents and hypotensive agents | WARNER-LAMBERT COMPANY (US) | 1991-01-29 | — | — | US | disclosed |