Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MC4R | P32245 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | MC3R | P41968 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 6/20 | 0.35 |
| ▸ | CA9 | Q16790 | 6/20 | 0.35 |
| ▸ | CA1 | P00915 | 5/20 | 0.35 |
| ▸ | CA12 | O43570 | 5/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | NAMPT | P43490 | 2/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4250361 | 0.80 | XDH (0.41) | HSP90AA1ADORA3TSHRMC4RADRA1A | |
| SCHEMBL21826839 | 0.79 | HDAC3 (0.36) | HSP90AA1ADORA3TSHRMC4RADRA1A | |
| SCHEMBL2400031 | 0.79 | HSP90AA1 (0.38) | HSP90AA1ADORA3TSHRMC4RADRA1A | |
| SCHEMBL31471242 | 0.79 | HDAC3 (0.39) | HSP90AA1ADORA3TSHRMC4RADRA1A | |
| SCHEMBL2400023 | 0.79 | HDAC3 (0.36) | HSP90AA1ADORA3TSHRMC4RADRA1A | |
| SCHEMBL4481303 | 0.79 | HDAC3 (0.39) | HSP90AA1ADORA3TSHRMC4RADRA1A | |
| SCHEMBL30437144 | 0.79 | HSP90AA1 (0.38) | HSP90AA1ADORA3TSHRMC4RADRA1A | |
| SCHEMBL25541266 | 0.76 | HDAC3 (0.37) | HSP90AA1ADORA3TSHRMC4RADRA1A | |
| SCHEMBL1273093 | 0.76 | HDAC3 (0.34) | HSP90AA1ADORA3TSHRMC4RADRA1A | |
| SCHEMBL24367867 | 0.75 | HDAC3 (0.36) | HDAC3HDAC1HDAC2HDAC6DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113490668-B | Compounds and compositions for the treatment of diseases associated with APJ receptor activity | 安娜普尔纳生物股份有限公司 | 2025-02-25 | — | — | CN | disclosed |
| US-20240336590-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH APJ RECEPTOR ACTIVITY | ANNAPURNA BIO, INC. | 2024-10-10 | — | — | US | disclosed |
| EP-4364798-A2 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH APJ RECEPTOR ACTIVITY | Annapurna Bio Inc. (US) | 2024-05-08 | — | — | EP | disclosed |
| US-11944622-B2 | Compounds and compositions for treating conditions associated with APJ receptor activity | ANNAPURNA BIO, INC. (US) | 2024-04-02 | — | — | US | disclosed |
| EP-3860998-B1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH APJ RECEPTOR ACTIVITY | ANNAPURNA BIO INC (US) | 2023-12-27 | — | — | EP | disclosed |
| US-11724997-B2 | Compounds and compositions for treating conditions associated with APJ receptor activity | ANNAPURNA BIO, INC. (US) | 2023-08-15 | — | — | US | disclosed |
| US-11724997-B2 | Compounds and compositions for treating conditions associated with APJ receptor activity | ANNAPURNA BIO, INC. (US) | 2023-08-15 | — | — | US | disclosed |
| US-11724997-B2 | Compounds and compositions for treating conditions associated with APJ receptor activity | ANNAPURNA BIO, INC. (US) | 2023-08-15 | — | — | US | disclosed |
| US-20230165854-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH APJ RECEPTOR ACTIVITY | SHOUTI INC. | 2023-06-01 | — | — | US | disclosed |
| US-20230165854-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH APJ RECEPTOR ACTIVITY | SHOUTI INC. | 2023-06-01 | — | — | US | disclosed |
| CN-112055713-A | Compounds and compositions for treating diseases associated with APJ receptor activity | 安娜普尔纳生物股份有限公司 | 2020-12-08 | — | — | CN | disclosed |
| WO-2020073011-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH APJ RECEPTOR ACTIVITY | ANNAPURNA BIO, INC. (US) | 2020-04-09 | — | — | WO | disclosed |
| WO-2020073011-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH APJ RECEPTOR ACTIVITY | ANNAPURNA BIO, INC. (US) | 2020-04-09 | — | — | WO | disclosed |
| CN-101970417-A | Substituted pyraz inylmethyl sulfonamides for use as. fungicides | BASF SE | 2011-02-09 | — | — | CN | disclosed |
| US-20110003691-A1 | Substituted Pyrazinylmethyl Sulfonamides For Use As Fungicides | BASF SE (DE) | 2011-01-06 | — | — | US | disclosed |
| US-20110003691-A1 | Substituted Pyrazinylmethyl Sulfonamides For Use As Fungicides | BASF SE (DE) | 2011-01-06 | — | — | US | disclosed |
| EP-2265592-A1 | SUBSTITUTED PYRAZ INYLMETHYL SULFONAMIDES FOR USE AS. FUNGICIDES | BASF SE (DE) | 2010-12-29 | — | — | EP | disclosed |
| EP-2265592-A1 | SUBSTITUTED PYRAZ INYLMETHYL SULFONAMIDES FOR USE AS. FUNGICIDES | BASF SE (DE) | 2010-12-29 | — | — | EP | disclosed |
| WO-2009112523-A1 | SUBSTITUTED PYRAZ INYLMETHYL SULFONAMIDES FOR USE AS. FUNGICIDES | BASF SE (DE) | 2009-09-17 | — | — | WO | disclosed |
| WO-2009112523-A1 | SUBSTITUTED PYRAZ INYLMETHYL SULFONAMIDES FOR USE AS. FUNGICIDES | BASF SE (DE) | 2009-09-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11724997-B2 | Compounds and compositions for treating conditions associated with APJ receptor activity | APLNR, AGTR1, AGTR2 | HSP90AA1 4031/4885ADORA3 240/4885TSHR 1266/4885 |
| US-20240336590-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH APJ RECEPTOR ACTIVITY | APLNR, AGTR1, AGTR2 | HSP90AA1 4031/4885ADORA3 240/4885TSHR 1266/4885 |
| US-20230165854-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH APJ RECEPTOR ACTIVITY | APLNR, AGTR1, AGTR2 | HSP90AA1 4043/4885ADORA3 201/4885TSHR 1332/4885 |
| US-20110003691-A1 | Substituted Pyrazinylmethyl Sulfonamides For Use As Fungicides | PRXL2A, ARSA, PADI1 | HSP90AA1 1862/4885ADORA3 602/4885TSHR 751/4885 |
| US-11944622-B2 | Compounds and compositions for treating conditions associated with APJ receptor activity | APLNR, AGTR1, AGTR2 | HSP90AA1 4043/4885ADORA3 201/4885TSHR 1332/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.