SCHEMBL987692

SCHEMBL987692

CC(CCN)NC(C)(C)C

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CACNA1F O60840 1/20 0.38
CHRM2 P08172 1/20 0.38
CHRM1 P11229 1/20 0.38
ADRA2B P18089 1/20 0.38
CHRM3 P20309 1/20 0.38
ADRA1A P35348 1/20 0.38
HRH1 P35367 1/20 0.38
OPRK1 P41145 1/20 0.38
CACNA1D Q01668 1/20 0.38
SLC6A3 Q01959 1/20 0.38
KCNH2 Q12809 1/20 0.38
CACNA1S Q13698 1/20 0.38
CACNA1C Q13936 1/20 0.38
SCN5A Q14524 1/20 0.38
GABRR1 P24046 2/20 0.32
GABBR2 O75899 2/20 0.31
GABBR1 Q9UBS5 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL988445 0.78
SCHEMBL24092090 0.78
SCHEMBL24092097 0.78
SCHEMBL14176514 0.76 CACNA1F (0.39) CACNA1FCHRM2CHRM1ADRA2BCHRM3
SCHEMBL7775114 0.76 CACNA1F (0.39) CACNA1FCHRM2CHRM1ADRA2BCHRM3
SCHEMBL24191898 0.74 CACNA1F (0.38) CACNA1FCHRM2CHRM1ADRA2BCHRM3
SCHEMBL24191893 0.74 CACNA1F (0.38) CACNA1FCHRM2CHRM1ADRA2BCHRM3
SCHEMBL9540629 0.74 CACNA1F (0.38) CACNA1FCHRM2CHRM1ADRA2BCHRM3
SCHEMBL25907461 0.74 CACNA1F (0.38) CACNA1FCHRM2CHRM1ADRA2BCHRM3
SCHEMBL19068778 0.72 CACNA1F (0.36) CACNA1FCHRM2CHRM1ADRA2BCHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 139 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12624303-B2 Gasoline additive composition for improved engine performance AFTON CHEMICAL CORPORATION (US) 2026-05-12 US disclosed
US-20260078313-A1 FUEL COMPOSITION SHELL USA INC (US) 2026-03-19 US disclosed
US-20260042971-A1 METHODS AND USES RELATING TO FUEL COMPOSITIONS INNOSPEC LTD (GB) 2026-02-12 US disclosed
EP-3690009-B1 FUEL ADDITIVE MIXTURE PROVIDING RAPID INJECTOR CLEAN-UP IN HIGH PRESSURE GASOLINE ENGINES AFTON CHEMICAL CORP (US) 2026-01-28 EP disclosed
EP-4663720-A1 PARTICULATE REDUCTION IN GDI ENGINES USING MANNICH DETERGENTS Afton Chemical Corporation (US) 2025-12-17 EP disclosed
US-20250376632-A1 PARTICULATE REDUCTION IN GDI ENGINES USING MANNICH DETERGENTS AFTON CHEMICAL CORP (US) 2025-12-11 US disclosed
US-12467008-B2 Methods and uses relating to fuel compositions INNOSPEC LIMITED (GB) 2025-11-11 US disclosed
EP-4345151-B1 GASOLINE ADDITIVE COMPOSITION FOR IMPROVED ENGINE PERFORMANCE AFTON CHEMICAL CORP (US) 2025-11-05 EP disclosed
US-12454653-B2 Gasoline additive composition for improved engine performance AFTON CHEMICAL CORPORATION (US) 2025-10-28 US disclosed
EP-4448699-B1 METHODS AND USES RELATING TO FUEL COMPOSITIONS INNOSPEC LTD (GB) 2025-09-03 EP disclosed
WO-2001042399-A1 FUELS COMPOSITIONS FOR DIRECT INJECTION GASOLINE ENGINES CONTAINING MANNICH DETERGENTS ETHYL CORPORATION (US) 2001-06-14 WO disclosed
WO-2001042398-A1 FUELS COMPOSITIONS FOR DIRECT INJECTION GASOLINE ENGINES CONTAINING MANGANESE COMPOUNDS ETHYL CORPORATION (US) 2001-06-14 WO disclosed
EP-1010747-A1 High-amine mannich dispersants for compression-ignition fuels ETHYL CORPORATION (US) 2000-06-21 EP disclosed
EP-1008642-A1 Fuels compositions containing polybutenes of narrow molecular weight distribution ETHYL CORPORATION (US) 2000-06-14 EP disclosed
US-6048373-A SPARK-IGNITION FUEL; A MANNICH DETERGENT; AND A POLYBUTENE HAVING A MOLECULAR WEIGHT DISTRIBUTION OF 1.4 OR LESS. ETHYL CORPORATION (US) 2000-04-11 US disclosed
US-5944858-A CONTAINING MANGANESE CARBONYL COMPOUND AND OVERBASED COMPOUND ETHYL PETROLEUM ADDITIVES, LTD. (GB) 1999-08-31 US disclosed
EP-0870819-A2 Additives for minimizing intake valve deposits, and their use ETHYL CORPORATION (US) 1998-10-14 EP disclosed
US-5725612-A A MANNICH REACTION PRODUCT FORMED BY POLYOLEFIN MODIFIED BY A POLYAMINE, ALDEHYDE AND PHENOLIC COMPOUND ETHYL CORPORATION (US) 1998-03-10 US disclosed
EP-0811672-A2 Additives for minimizing intake valve deposits, and their use ETHYL CORPORATION (US) 1997-12-10 EP disclosed
US-5634951-A FUEL ADDITIVE COMPRISING THE MANNICH CONDENSATION PRODUCT OF A POLYOLEFIN-ALKYLATED PHENOL, AN ALKYLENE DIAMINE AND AN ALDEHYDE; SPARK-IGNITED INTERNAL COMBUSTION ENGINES; ANTISTICKING AGENTS ETHYL CORPORATION (US) 1997-06-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12624303-B2 Gasoline additive composition for improved engine performance SEM1, SUMO2, TAF1 CACNA1F 600/4885CHRM2 399/4885CHRM1 559/4885
US-20260042971-A1 METHODS AND USES RELATING TO FUEL COMPOSITIONS SDHA, SDHB, IDH3B CACNA1F 103/4885CHRM2 1506/4885CHRM1 1341/4885
US-20260078313-A1 FUEL COMPOSITION SRM, SMOX, SMS CACNA1F 2099/4885CHRM2 225/4885CHRM1 69/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.