Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.69 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.67 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 11/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.63 |
| ▸ | RAB9A | P51151 | 2/20 | 0.63 |
| ▸ | GAA | P10253 | 2/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | QPCT | Q16769 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9877025 | 0.84 | RECQL (0.67) | RECQLHPGDALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL24797472 | 0.81 | ALDH1A1 (1.00) | HPGDALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL1548213 | 0.77 | ALDH1A1 (0.69) | HPGDALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL30725947 | 0.77 | ALDH1A1 (0.69) | HPGDALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4578714 | 0.75 | CLK2 (0.65) | RECQLHPGDALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL14434248 | 0.74 | ALDH1A1 (1.00) | HPGDALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6689373 | 0.73 | ROCK2 (0.58) | RECQLHPGDALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL23084085 | 0.73 | RECQL (0.66) | RECQLHPGDALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL7572900 | 0.73 | INSR (0.56) | HPGDALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8774349 | 0.73 | ALDH1A1 (0.67) | HPGDALDH1A1CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4997667-A | Pyridinyl compounds of N-carbamoyl-N-thiocarbamoyl- or N-amidino-glycine or beta-alanine useful as sweetening agents | UNIVERSITE CLAUDE BERNARD (FR) | 1991-03-05 | — | — | US | disclosed |
| EP-0321369-A1 | Heterocyclic sweeteners derived from N-carbamoyl-, N-thiocarbamoyl or N-amidino-glycine or beta-alanine | UNIVERSITE CLAUDE BERNARD - LYON 1 (FR) | 1989-06-21 | — | — | EP | disclosed |