Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9877903 | 0.93 | ALDH1A1 (0.59) | KMT2ATSHRTDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9878201 | 0.89 | KAT2B (0.46) | KMT2ATSHRTDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9878286 | 0.85 | MAPT (0.60) | KMT2ATSHRALDH1A1SMN1; SMN2PKM | |
| SCHEMBL10851653 | 0.83 | KMT2A (0.60) | KMT2ATSHRTDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9877920 | 0.82 | CYP19A1 (0.44) | TDP1ALDH1A1SMN1; SMN2PKMMAPT | |
| SCHEMBL10536600 | 0.82 | KMT2A (0.59) | KMT2ATSHRTDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL29597632 | 0.81 | KMT2A (0.58) | KMT2ATSHRTDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9877922 | 0.81 | KMT2A (0.58) | KMT2ATSHRTDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9878326 | 0.81 | ALDH1A1 (0.56) | KMT2ATDP1ALDH1A1SMN1; SMN2PKM | |
| SCHEMBL9879008 | 0.80 | CYP19A1 (0.42) | KMT2ATDP1ALDH1A1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992589-A | Substituted phenyl hydroxyethyl sulfones, and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-02-12 | — | — | US | disclosed |