Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 3/20 | 0.43 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9877927 | 0.93 | KMT2A (0.54) | ALDH1A1SMN1; SMN2KMT2ATSHRTDP1 | |
| SCHEMBL9878201 | 0.87 | KAT2B (0.46) | ALDH1A1SMN1; SMN2KMT2ATSHRTDP1 | |
| SCHEMBL9878286 | 0.83 | MAPT (0.60) | ALDH1A1SMN1; SMN2KMT2ATSHRPKM | |
| SCHEMBL9877899 | 0.81 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2KMT2ATSHRTDP1 | |
| SCHEMBL9879146 | 0.80 | CYP19A1 (0.40) | ALDH1A1SMN1; SMN2KMT2ATDP1MAPT | |
| SCHEMBL9877920 | 0.80 | CYP19A1 (0.44) | ALDH1A1SMN1; SMN2TDP1PKMMAPT | |
| SCHEMBL9878326 | 0.79 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2KMT2ATDP1PKM | |
| SCHEMBL23609612 | 0.78 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2KMT2ATSHRTDP1 | |
| SCHEMBL9879008 | 0.78 | CYP19A1 (0.42) | ALDH1A1SMN1; SMN2KMT2ATDP1MAPT | |
| SCHEMBL14003611 | 0.77 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2KMT2ATSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992589-A | Substituted phenyl hydroxyethyl sulfones, and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-02-12 | — | — | US | disclosed |