SCHEMBL9879110

SCHEMBL9879110

O=C1NCC[S+]([O-])c2ccccc21

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 11/20 0.46
PARP11 Q9NR21 7/20 0.46
PARP10 Q53GL7 6/20 0.46
PDPK1 O15530 1/20 0.46
CA12 O43570 1/20 0.40
CA9 Q16790 1/20 0.40
GSK3B P49841 1/20 0.34
GRM5 P41594 1/20 0.33
PIM1 P11309 1/20 0.33
CSNK1A1 P48729 1/20 0.33
CDK5 Q00535 1/20 0.33
ROCK1 Q13464 1/20 0.33
DYRK1A Q13627 1/20 0.33
LRRK2 Q5S007 1/20 0.33
CLK4 Q9HAZ1 1/20 0.33
DYRK1B Q9Y463 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3493955 0.73 MAOA (0.41) PARP1PARP11PARP10PDPK1GSK3B
SCHEMBL88860 0.73 MEN1 (0.34)
SCHEMBL181833 0.67 MEN1 (0.35) GSK3B
SCHEMBL4455970 0.66 PARP1 (0.57) PARP1PARP11PARP10PDPK1CA12
SCHEMBL700485 0.65 PARP10 (0.55) PARP1PARP11PARP10PDPK1CA12
SCHEMBL10196632 0.64
SCHEMBL67710 0.63 PARP10 (1.00) PARP1PARP11PARP10PDPK1CA12
SCHEMBL3296103 0.63 PARP11 (0.64) PARP1PARP11PARP10PDPK1CA12
Hydrochloric Acid SCHEMBL30124058 0.63 PARP10 (0.53) PARP1PARP11PARP10PDPK1CA12
SCHEMBL29369705 0.63 PARP10 (1.00) PARP1PARP11PARP10PDPK1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4990707-A Process for the ring chlorination of aromatic hydrocarbons BAYER AKTIENGESELLSCHAFT (DE) 1991-02-05 US disclosed