Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7347184 | 0.88 | MEN1 (0.32) | MEN1GAAKMT2AALDH1A1 | |
| SCHEMBL13477741 | 0.88 | MEN1 (0.32) | MEN1GAAKMT2AALDH1A1 | |
| SCHEMBL9630852 | 0.86 | MEN1 (0.32) | MEN1GAAKMT2AALDH1A1 | |
| SCHEMBL83412 | 0.78 | ALOX15 (0.30) | — | |
| Hydrochloric Acid SCHEMBL9449441 | 0.77 | MEN1 (0.31) | MEN1GAAKMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL27353718 | 0.77 | MEN1 (0.31) | MEN1GAAKMT2AALDH1A1 | |
| SCHEMBL4622490 | 0.77 | — | — | |
| SCHEMBL20100281 | 0.75 | CHRNB2 (0.32) | — | |
| SCHEMBL9879110 | 0.73 | PARP1 (0.46) | — | |
| SCHEMBL7347191 | 0.71 | MEN1 (0.32) | MEN1GAAKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 443 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119285574-A | Method for preparing 3, 4-dihydro-2H-benzo [ b ] [1,4] thiazine-1-oxide by cooperation of monopersulfate | 绍兴文理学院 | 2025-01-10 | — | — | CN | claimed |
| CN-119285574-A | Method for preparing 3, 4-dihydro-2H-benzo [ b ] [1,4] thiazine-1-oxide by cooperation of monopersulfate | 绍兴文理学院 | 2025-01-10 | — | — | CN | disclosed |
| CN-119285574-A | Method for preparing 3, 4-dihydro-2H-benzo [ b ] [1,4] thiazine-1-oxide by cooperation of monopersulfate | 绍兴文理学院 | 2025-01-10 | — | — | CN | disclosed |
| CN-119285574-A | Method for preparing 3, 4-dihydro-2H-benzo [ b ] [1,4] thiazine-1-oxide by cooperation of monopersulfate | 绍兴文理学院 | 2025-01-10 | — | — | CN | disclosed |
| WO-2024126453-A1 | NEW SUBSTITUTED INDOLE-2-CARBOXAMIDES AS PHGDH INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2024-06-20 | — | — | WO | disclosed |
| WO-2024089006-A1 | HETEROCYCLIC COMPOUNDS CAPABLE OF ACTIVATING STING | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2024-05-02 | — | — | WO | disclosed |
| WO-2024089008-A1 | HETEROCYCLIC COMPOUNDS CAPABLE OF ACTIVATING STING | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2024-05-02 | — | — | WO | disclosed |
| WO-2024088991-A1 | HETEROCYCLIC COMPOUNDS CAPABLE OF ACTIVATING STING | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2024-05-02 | — | — | WO | disclosed |
| WO-2024089155-A1 | HETEROCYCLIC COMPOUNDS AS STING ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2024-05-02 | — | — | WO | disclosed |
| US-11814380-B2 | Benzylamino substituted pyridopyrimidinones and derivatives as SOS1 inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2023-11-14 | — | — | US | disclosed |
| US-20090312304-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2009-12-17 | — | — | US | disclosed |
| US-20090281161-A1 | Organic Compounds | MAIBAUM JUERGEN KLAUS | 2009-11-12 | — | — | US | disclosed |
| US-20090270417-A1 | Organic Compounds | NOVARTIS AG (CH) | 2009-10-29 | — | — | US | disclosed |
| US-20090247577-A1 | PYRROLIDINE DERIVATIVES USEFUL AS BACE INHIBITORS | ROGEL OLIVIER | 2009-10-01 | — | — | US | disclosed |
| US-20090233920-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2009-09-17 | — | — | US | disclosed |
| US-7576099-B2 | Amide derivatives as ion-channel ligands and pharmaceutical compositions and methods of using the same | RENOVIS, INC. (US) | 2009-08-18 | — | — | US | disclosed |
| US-7576099-B2 | Amide derivatives as ion-channel ligands and pharmaceutical compositions and methods of using the same | RENOVIS, INC. (US) | 2009-08-18 | — | — | US | disclosed |
| US-20090192148-A1 | Organic Compounds | NOVARTIS AG (CH) | 2009-07-30 | — | — | US | disclosed |
| EP-1027347-A2 | 3-AMINOALKYLAMINO-2H-1,4-BENZOXA(THIA-)ZINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | NEUROGEN CORPORATION (US) | 2000-08-16 | — | — | EP | disclosed |
| WO-1999023092-A2 | 3-AMINOALKYLAMINO-2H-1,4-BENZOXA(THIA-)ZINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | NEUROGEN CORPORATION (US) | 1999-05-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090247577-A1 | PYRROLIDINE DERIVATIVES USEFUL AS BACE INHIBITORS | BACE1, BACE2, APP | MEN1 2753/4885GAA 47/4885KMT2A 3683/4885 |
| US-20090233920-A1 | ORGANIC COMPOUNDS | REN, ACE, AGTR1 | MEN1 2386/4885GAA 353/4885KMT2A 3192/4885 |
| US-20090192148-A1 | Organic Compounds | REN, ACE, AGTR1 | MEN1 2336/4885GAA 309/4885KMT2A 3129/4885 |
| US-20090281161-A1 | Organic Compounds | REN, ACE, OTC | MEN1 2965/4885GAA 147/4885KMT2A 3953/4885 |
| US-20090270417-A1 | Organic Compounds | REN, ACE, OTC | MEN1 2965/4885GAA 147/4885KMT2A 3953/4885 |
| US-11814380-B2 | Benzylamino substituted pyridopyrimidinones and derivatives as SOS1 inhibitors | SOS1, SOST, BMP1 | MEN1 112/4885GAA 3390/4885KMT2A 2989/4885 |
| US-20090312304-A1 | ORGANIC COMPOUNDS | REN, ACE, PIGO | MEN1 2792/4885GAA 78/4885KMT2A 3979/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.