SCHEMBL9879882

SCHEMBL9879882

C=CCc1ccc(-c2ccccc2C(=O)C(=O)c2ccccc2-c2ccc(CC=C)cc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTB4R2 Q9NPC1 6/20 0.41
BCAT2 O15382 1/20 0.41
CHRNB2 P17787 1/20 0.41
CHRNB4 P30926 1/20 0.41
CHRNA3 P32297 1/20 0.41
CHRNA4 P43681 1/20 0.41
GPR52 Q9Y2T5 1/20 0.40
MEN1 O00255 4/20 0.40
KMT2A Q03164 4/20 0.40
ALDH1A1 P00352 2/20 0.40
GAA P10253 2/20 0.40
MAPT P10636 2/20 0.40
GABRA1 P14867 2/20 0.40
CNR1 P21554 2/20 0.40
CNR2 P34972 2/20 0.40
GABRB2 P47870 2/20 0.40
KDM4E B2RXH2 1/20 0.40
ALDH2 P05091 1/20 0.40
AKR1B1 P15121 1/20 0.40
HPGD P15428 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8731770 0.89 LTB4R2 (0.54) LTB4R2
SCHEMBL8734298 0.87 BCAT2 (0.59) LTB4R2BCAT2CHRNB2CHRNB4CHRNA3
SCHEMBL9879883 0.82 LTB4R2 (0.41) LTB4R2GPR52MEN1KMT2AALDH1A1
SCHEMBL10447744 0.81 CYP3A4 (0.60) CHRNB2CHRNB4CHRNA3CHRNA4MEN1
SCHEMBL28301907 0.77 GABRA1 (0.56) MEN1KMT2AALDH1A1GAAMAPT
SCHEMBL584382 0.75 GABRA1 (0.48) MEN1KMT2AALDH1A1GAAMAPT
SCHEMBL8734418 0.75 ALOX5 (0.46) MEN1KMT2AALDH1A1GAAPPARG
SCHEMBL8729853 0.75 XDH (0.45) MEN1KMT2AALDH1A1GAAMAPT
SCHEMBL8734481 0.74 ALOX5 (0.45) MEN1KMT2AALDH1A1GAAKDM4E
SCHEMBL28880915 0.74 ALDH1A1 (0.44) MEN1KMT2AALDH1A1GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0409437-A2 Process for preparing aromatic polycarboxylic acids KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1991-01-23 EP disclosed