SCHEMBL9885111

SCHEMBL9885111

COC1OC(C(=O)O)C(OC2OC(C(=O)O)C(C)C(O)C2O)C(O)C1O

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ F10 P00742 6/20 0.39
▸ M6PR P20645 2/20 0.35
▸ FGF1 P05230 3/20 0.35
▸ CXCL10 P02778 1/20 0.34
▸ CXCL8 P10145 1/20 0.34
▸ CCL2 P13500 1/20 0.34
▸ CCL5 P13501 1/20 0.34
▸ CXCL12 P48061 1/20 0.34
▸ LGALS8 O00214 2/20 0.33
▸ BDNF P23560 3/20 0.32
▸ PTN P21246 2/20 0.32
▸ MDK P21741 2/20 0.32
▸ SERPINC1 P01008 1/20 0.31
▸ LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19441368 1.00 F10 (0.39) F10M6PRFGF1CXCL10CXCL8
SCHEMBL14586220 1.00 F10 (0.39) F10M6PRFGF1CXCL10CXCL8
SCHEMBL12878540 0.89 F10 (0.43) F10M6PRFGF1CXCL10CXCL8
SCHEMBL22139521 0.89 F10 (0.43) F10M6PRFGF1CXCL10CXCL8
SCHEMBL17739731 0.89 F10 (0.43) F10M6PRFGF1CXCL10CXCL8
SCHEMBL12458629 0.89 F10 (0.43) F10M6PRFGF1CXCL10CXCL8
SCHEMBL20370858 0.89 F10 (0.43) F10M6PRFGF1CXCL10CXCL8
SCHEMBL12384884 0.89 F10 (0.43) F10M6PRFGF1CXCL10CXCL8
SCHEMBL12755226 0.89 F10 (0.43) F10M6PRFGF1CXCL10CXCL8
SCHEMBL20363547 0.89 F10 (0.43) F10M6PRFGF1CXCL10CXCL8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160137503-A1 HIGHLY POROUS AEROGELS NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2016-05-19 — — US disclosed
US-8389661-B2 Complexes between an amphiphilic polymer and an osteogenic protein belonging to the family of BMPs ADOCIA (FR) 2013-03-05 — — US disclosed
US-8192987-B2 Human dental follicle stem cells and methods for obtaining TISSUEDENT GMBH & CO. KG (DE) 2012-06-05 — — US disclosed
US-20100062232-A1 MULTILAYER FILMS DREXEL UNIVERSITY (US) 2010-03-11 — — US disclosed
US-20090221805-A1 Complex polymere amphiphile-PDGF PROTEINS AND PEPTIDES MANAGEMENT (FR) 2009-09-03 — — US disclosed
US-20090048412-A1 Complexes between an amphiphilic polymer and an osteogenic protein belonging to the family of BMPs ADOCIA (FR) 2009-02-19 — — US disclosed
US-20090035282-A1 Pluripotent embryonic-like stem cells derived from teeth and uses thereof STIFTUNG CAESAR 2009-02-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090035282-A1 Pluripotent embryonic-like stem cells derived from teeth and uses thereof ALPG, WAPL, SALL4 F10 4417/4885M6PR 2531/4885FGF1 241/4885
US-20090221805-A1 Complex polymere amphiphile-PDGF PDGFA, PDGFRA, FIBP F10 1363/4885M6PR 1532/4885FGF1 98/4885
US-20090048412-A1 Complexes between an amphiphilic polymer and an osteogenic protein belonging to the family of BMPs BMP2, BMP1, BMP6 F10 246/4885M6PR 254/4885FGF1 76/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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