SCHEMBL9889159

SCHEMBL9889159

c1ccc(N(c2ccccc2)c2ccc(-c3ccc4c5ccccc5c5ccccc5c4c3)cc2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
KDM4E B2RXH2 2/20 0.45
CYP1A2 P05177 2/20 0.45
CYP3A4 P08684 2/20 0.45
CYP2D6 P10635 2/20 0.45
MAPT P10636 2/20 0.45
CYP2C19 P33261 2/20 0.45
TDP1 Q9NUW8 2/20 0.45
CYP2C9 P11712 1/20 0.45
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
CRHBP P24387 1/20 0.38
ATM Q13315 1/20 0.38
CRHR2 Q13324 1/20 0.38
TLR9 Q9NR96 1/20 0.38
APP P05067 2/20 0.37
ALOX5 P09917 1/20 0.34
PKM P14618 1/20 0.34
JAK2 O60674 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12153409 1.00 ALDH1A1 (0.45) ALDH1A1L3MBTL1KDM4ECYP1A2CYP3A4
SCHEMBL12395688 1.00 ALDH1A1 (0.45) ALDH1A1L3MBTL1KDM4ECYP1A2CYP3A4
SCHEMBL12395682 1.00 ALDH1A1 (0.45) ALDH1A1L3MBTL1KDM4ECYP1A2CYP3A4
SCHEMBL16437941 0.98 ALDH1A1 (0.43) ALDH1A1L3MBTL1KDM4ECYP1A2CYP3A4
SCHEMBL15306287 0.98 ALDH1A1 (0.43) ALDH1A1L3MBTL1KDM4ECYP1A2CYP3A4
SCHEMBL15294224 0.98 ALDH1A1 (0.43) ALDH1A1L3MBTL1KDM4ECYP1A2CYP3A4
SCHEMBL16437944 0.98 ALDH1A1 (0.43) ALDH1A1L3MBTL1KDM4ECYP1A2CYP3A4
SCHEMBL12395685 0.98 ALDH1A1 (0.43) ALDH1A1L3MBTL1KDM4ECYP1A2CYP3A4
SCHEMBL12395686 0.98 ALDH1A1 (0.43) ALDH1A1L3MBTL1KDM4ECYP1A2CYP3A4
SCHEMBL12395693 0.98 ALDH1A1 (0.43) ALDH1A1L3MBTL1KDM4ECYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10985325-B2 Aromatic amine derivative, and organic electroluminescent element using same IDEMITSU KOSAN CO., LTD. (JP) 2021-04-20 US disclosed
US-10193077-B2 Biscarbazole derivative, material for organic electroluminescence device and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2019-01-29 US disclosed
EP-3312167-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME Idemitsu Kosan Co., Ltd. (JP) 2018-04-25 EP disclosed
US-20150263292-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2015-09-17 US disclosed
US-20150263292-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2015-09-17 US disclosed
US-20150228912-A1 BISCARBAZOLE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2015-08-13 US disclosed
US-20150228912-A1 BISCARBAZOLE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2015-08-13 US disclosed
US-20150194622-A1 BISCARBAZOLE DERIVATIVE HOST MATERIALS AND RED EMITTER FOR OLED EMISSIVE REGION IDEMITSU KOSAN CO., LTD. (JP) 2015-07-09 US disclosed
US-20150194622-A1 BISCARBAZOLE DERIVATIVE HOST MATERIALS AND RED EMITTER FOR OLED EMISSIVE REGION IDEMITSU KOSAN CO., LTD. (JP) 2015-07-09 US disclosed
US-8940414-B2 Biscarbazole derivative, material for organic electroluminescence device and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2015-01-27 US disclosed
US-20120199820-A1 MONOAMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-08-09 US disclosed
US-20120199820-A1 MONOAMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-08-09 US disclosed
US-20120138911-A1 BISCARBAZOLE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. 2012-06-07 US disclosed
US-20120138911-A1 BISCARBAZOLE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. 2012-06-07 US disclosed
US-20120138912-A1 BISCARBAZOLE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. 2012-06-07 US disclosed
US-20120138912-A1 BISCARBAZOLE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. 2012-06-07 US disclosed
US-20110279020-A1 Biscarbazole Derivative, Material for Organic Electroluminescence Device and Organic Electroluminescence Device Using The Same IDEMITSU KOSAN CO., LTD. 2011-11-17 US disclosed
US-20110278555-A1 BISCARBAZOLE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. 2011-11-17 US disclosed
US-20110278555-A1 BISCARBAZOLE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. 2011-11-17 US disclosed
US-20110279020-A1 Biscarbazole Derivative, Material for Organic Electroluminescence Device and Organic Electroluminescence Device Using The Same IDEMITSU KOSAN CO., LTD. 2011-11-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120199820-A1 MONOAMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME MAOA, ADRA1A, ADRA1D ALDH1A1 102/4885L3MBTL1 3069/4885KDM4E 633/4885
US-20120138911-A1 BISCARBAZOLE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME UQCRB, OXA1L, HBS1L ALDH1A1 362/4885L3MBTL1 1447/4885KDM4E 1058/4885
US-20150263292-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME RER1, H1-2, NAP1L1 ALDH1A1 30/4885L3MBTL1 71/4885KDM4E 995/4885
US-10985325-B2 Aromatic amine derivative, and organic electroluminescent element using same RER1, H1-2, NAP1L1 ALDH1A1 30/4885L3MBTL1 71/4885KDM4E 995/4885
US-20110278555-A1 BISCARBAZOLE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME UQCRB, OXA1L, HBS1L ALDH1A1 362/4885L3MBTL1 1447/4885KDM4E 1058/4885
US-20120138912-A1 BISCARBAZOLE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME UQCRB, OXA1L, HBS1L ALDH1A1 380/4885L3MBTL1 1516/4885KDM4E 984/4885
US-20110279020-A1 Biscarbazole Derivative, Material for Organic Electroluminescence Device and Organic Electroluminescence Device Using The Same UQCRB, OXA1L, HBS1L ALDH1A1 380/4885L3MBTL1 1516/4885KDM4E 984/4885
US-10193077-B2 Biscarbazole derivative, material for organic electroluminescence device and organic electroluminescence device using the same UQCRB, OXA1L, HBS1L ALDH1A1 380/4885L3MBTL1 1516/4885KDM4E 984/4885
US-20150228912-A1 BISCARBAZOLE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME UQCRB, OXA1L, HBS1L ALDH1A1 380/4885L3MBTL1 1516/4885KDM4E 984/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.