SCHEMBL9889355

SCHEMBL9889355

CCN(C)C(=N)NP(=O)(O)O

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
FDPS P14324 1/20 0.33
MMP1 P03956 1/20 0.33
MMP2 P08253 1/20 0.33
MMP3 P08254 1/20 0.33
MMP8 P22894 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9889356 0.83 FDPS (0.38) FDPSMMP1MMP2MMP3MMP8
SCHEMBL9889350 0.78
Fosfocreatine SCHEMBL5906913 0.78 MVD (0.36)
Fosfocreatine SCHEMBL9319921 0.77 MVD (0.41)
Fosfocreatine SCHEMBL65424 0.77 MVD (0.41)
Fosfocreatine SCHEMBL612833 0.75 MVD (0.40)
SCHEMBL7827185 0.75 PHF8 (0.35)
Fosfocreatine SCHEMBL21381775 0.75 MVD (0.40)
Fosfocreatine SCHEMBL3026725 0.75 MVD (0.40)
Fosfocreatine SCHEMBL1640491 0.75 MVD (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230285338-A9 METHODS FOR TREATING MICROGLIAL DYSFUNCTION WASHINGTON UNIVERSITY 2023-09-14 US disclosed
US-20210393563-A1 METHODS FOR TREATING MICROGLIAL DYSFUNCTION NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2021-12-23 US disclosed
US-9434753-B2 Modified creatine compounds GENCIA CORPORATION (US) 2016-09-06 US disclosed
US-20150005258-A1 Modified Creatine Compounds Genci Corporation (US) 2015-01-01 US disclosed
US-20140045798-A1 MITOCHONDRIAL COMPOSITIONS AND USES THEREOF GENCIA CORPORATION (US) 2014-02-13 US disclosed
US-20130072462-A1 Mitochondrial Compositions and Uses Thereof GENCIA CORPORATION (US) 2013-03-21 US disclosed
US-20120141391-A1 Use of creatine or creatine compounds for skin preservation AVICENA GROUP, INC. (US) 2012-06-07 US disclosed
US-20110085993-A1 USE OF CREATINE OR CREATINE COMPOUNDS FOR SKIN PRESERVATION AVICENA GROUP, INC. (US) 2011-04-14 US disclosed
US-20110021632-A1 USE OF CREATINE OR CREATINE COMPOUNDS FOR SKIN PRESERVATION AVICENA GROUP, INC. (US) 2011-01-27 US disclosed
US-20110008272-A1 Use of Creatine or Creatine Compounds for Skin Preservation AVICENA GROUP, INC. (US) 2011-01-13 US disclosed
US-20100329997-A1 USE OF CREATINE OR CREATINE COMPOUNDS FOR SKIN PRESERVATION AVICENA GROUP, INC. (US) 2010-12-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140045798-A1 MITOCHONDRIAL COMPOSITIONS AND USES THEREOF CS, UQCRC1, UQCRC2 FDPS 522/4885MMP1 1967/4885MMP2 1876/4885
US-20110008272-A1 Use of Creatine or Creatine Compounds for Skin Preservation PC, CKMT1A; CKMT1B, CHEK1 FDPS 1295/4885MMP1 1796/4885MMP2 1970/4885
US-20120141391-A1 Use of creatine or creatine compounds for skin preservation PC, CKMT1A; CKMT1B, CHEK1 FDPS 1295/4885MMP1 1796/4885MMP2 1970/4885
US-20100329997-A1 USE OF CREATINE OR CREATINE COMPOUNDS FOR SKIN PRESERVATION PC, CKMT1A; CKMT1B, CHEK1 FDPS 1295/4885MMP1 1796/4885MMP2 1970/4885
US-20110021632-A1 USE OF CREATINE OR CREATINE COMPOUNDS FOR SKIN PRESERVATION PC, CKMT1A; CKMT1B, CHEK1 FDPS 1295/4885MMP1 1796/4885MMP2 1970/4885
US-20210393563-A1 METHODS FOR TREATING MICROGLIAL DYSFUNCTION CHRNB2, PSEN2, CX3CR1 FDPS 3961/4885MMP1 2018/4885MMP2 1988/4885
US-20110085993-A1 USE OF CREATINE OR CREATINE COMPOUNDS FOR SKIN PRESERVATION PC, CKMT1A; CKMT1B, CHEK1 FDPS 1295/4885MMP1 1796/4885MMP2 1970/4885
US-20230285338-A9 METHODS FOR TREATING MICROGLIAL DYSFUNCTION CX3CR1, CD68, FYN FDPS 4112/4885MMP1 1789/4885MMP2 2247/4885
US-20130072462-A1 Mitochondrial Compositions and Uses Thereof UQCRC1, CS, UQCRC2 FDPS 578/4885MMP1 2274/4885MMP2 2078/4885
US-20150005258-A1 Modified Creatine Compounds CKMT1A; CKMT1B, SLC25A20, ARG2 FDPS 3562/4885MMP1 3157/4885MMP2 2103/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.