SCHEMBL9890744

SCHEMBL9890744

Cc1ccc(F)cc1-c1ccccc1CC(N)=O

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SLC9A1 P19634 2/20 0.41
ICMT O60725 7/20 0.40
MAPK14 Q16539 1/20 0.39
RXRA P19793 1/20 0.39
PPARG P37231 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.36
PKM P14618 1/20 0.36
MAPT P10636 1/20 0.36
CSNK1D P48730 1/20 0.36
LMNA P02545 1/20 0.35
ABL1 P00519 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2393136 0.85 SLC9A1 (0.42) SLC9A1ICMTSMN1; SMN2PKMMAPT
SCHEMBL9890752 0.83 SMN1; SMN2 (0.42) RXRAPPARGSMN1; SMN2PKMMAPT
SCHEMBL9890710 0.82 FFAR1 (0.43) SLC9A1ICMTMAPT
SCHEMBL2394997 0.82 DPP4 (0.40) ICMTMAPK14PKM
SCHEMBL12265632 0.82 CHRM1 (0.46) ICMTMAPT
SCHEMBL9890790 0.82 PKM (0.40) SLC9A1ICMTSMN1; SMN2PKMMAPT
SCHEMBL9892664 0.80 CHRM5 (0.41) ICMTMAPTLMNA
SCHEMBL2090788 0.79 ICMT (0.46) SLC9A1ICMT
SCHEMBL2395132 0.79 ICMT (0.39) SLC9A1ICMTPPARGMAPT
SCHEMBL2393938 0.78 KCNA5 (0.37) ICMTPKMLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120142771-A1 BIPHENYLACETAMIDE DERIVATIVE DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) 2012-06-07 US disclosed
US-20110224304-A1 BIPHENYLACETAMIDE DERIVATIVE DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) 2011-09-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120142771-A1 BIPHENYLACETAMIDE DERIVATIVE HRH3, KCNH3, BRPF3 SLC9A1 132/4885ICMT 2894/4885MAPK14 1382/4885
US-20110224304-A1 BIPHENYLACETAMIDE DERIVATIVE HRH3, KCNH3, BRPF3 SLC9A1 132/4885ICMT 2894/4885MAPK14 1382/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.