SCHEMBL9890832

SCHEMBL9890832

Cc1ccc(-c2c3ccccc3c(-c3cccc4c3oc3ccccc34)c3ccccc23)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.51
MAOB P27338 2/20 0.43
TNKS O95271 1/20 0.43
PARP1 P09874 1/20 0.43
TNKS2 Q9H2K2 1/20 0.43
PARP2 Q9UGN5 1/20 0.43
HTT P42858 2/20 0.41
LMNA P02545 1/20 0.41
TP53 P04637 1/20 0.41
RET P07949 1/20 0.41
TSHR P16473 1/20 0.41
ALOX12 P18054 1/20 0.41
KDR P35968 1/20 0.41
GGPS1 O95749 1/20 0.38
PGR P06401 1/20 0.38
PRKDC P78527 4/20 0.38
ACHE P22303 1/20 0.38
KDM4E B2RXH2 3/20 0.37
ALDH1A1 P00352 3/20 0.37
SMN1; SMN2 Q16637 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1687986 0.94 ALOX5 (0.55) ALOX5MAOBTNKSPARP1TNKS2
SCHEMBL21450762 0.92 ALOX5 (0.58) ALOX5LMNATSHRGGPS1PGR
SCHEMBL21450768 0.91 ALOX5 (0.56) ALOX5GGPS1PRKDCPIK3CDPIK3CB
SCHEMBL9890844 0.89 ALOX5 (0.57) ALOX5MAOBTNKSPARP1TNKS2
SCHEMBL13488349 0.88 ALOX5 (0.47) ALOX5MAOBTNKSPARP1TNKS2
SCHEMBL126586 0.88 ALOX5 (0.54) ALOX5LMNATSHRGGPS1PRKDC
SCHEMBL22854818 0.88 ALOX5 (0.54) ALOX5LMNATSHRGGPS1PRKDC
SCHEMBL25575733 0.88 ALOX5 (0.43) ALOX5MAOBTNKSPARP1TNKS2
SCHEMBL13488344 0.88 ALOX5 (0.46) ALOX5MAOBTNKSPARP1TNKS2
SCHEMBL25575756 0.88 ALOX5 (0.43) ALOX5MAOBTNKSPARP1TNKS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018128470-A1 ORGANIC ELECTROLUMINESCENT ELEMENT 머티어리얼사이언스 주식회사 2018-07-12 WO disclosed
US-8502201-B2 Light-emitting element TORAY INDUSTRIES, INC. (JP) 2013-08-06 US disclosed
US-8502201-B2 Light-emitting element TORAY INDUSTRIES, INC. (JP) 2013-08-06 US disclosed
US-20120138907-A1 LIGHT-EMITTING DEVICE MATERIAL AND LIGHT-EMITTING DEVICE TORAY INDUSTRIES, INC. (JP) 2012-06-07 US disclosed
US-20120138907-A1 LIGHT-EMITTING DEVICE MATERIAL AND LIGHT-EMITTING DEVICE TORAY INDUSTRIES, INC. (JP) 2012-06-07 US disclosed
US-8084146-B2 Light-emitting device material and light-emitting device TORAY INDUSTRIES, INC. (JP) 2011-12-27 US disclosed
US-8084146-B2 Light-emitting device material and light-emitting device TORAY INDUSTRIES, INC. (JP) 2011-12-27 US disclosed
US-20110248217-A1 ELECTROLUMINESCENT DEVICE UDC IRELAND LIMITED (IE) 2011-10-13 US disclosed
US-20110248217-A1 ELECTROLUMINESCENT DEVICE UDC IRELAND LIMITED (IE) 2011-10-13 US disclosed
US-20110121268-A1 LIGHT-EMITTING ELEMENT TORAY INDUSTRIES, INC. (JP) 2011-05-26 US disclosed
US-20110121268-A1 LIGHT-EMITTING ELEMENT TORAY INDUSTRIES, INC. (JP) 2011-05-26 US disclosed
US-7901794-B2 Material for light-emitting element and light emitting element TORAY INDUSTRIES, INC. (JP) 2011-03-08 US disclosed
US-7901794-B2 Material for light-emitting element and light emitting element TORAY INDUSTRIES, INC. (JP) 2011-03-08 US disclosed
US-20090066245-A1 MATERIAL FOR LIGHT-EMITTING ELEMENT AND LIGHT EMITTING ELEMENT TORAY INDUSTRIES, INC. (JP) 2009-03-12 US disclosed
US-20090066245-A1 MATERIAL FOR LIGHT-EMITTING ELEMENT AND LIGHT EMITTING ELEMENT TORAY INDUSTRIES, INC. (JP) 2009-03-12 US disclosed
US-20070247063-A1 Light-Emitting Device Material and Light-Emitting Device TORAY INDUSTRIES INC. (JP) 2007-10-25 US disclosed
US-20070247063-A1 Light-Emitting Device Material and Light-Emitting Device TORAY INDUSTRIES INC. (JP) 2007-10-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110248217-A1 ELECTROLUMINESCENT DEVICE DDT, CD99, EED ALOX5 741/4885MAOB 186/4885TNKS 4666/4885
US-20120138907-A1 LIGHT-EMITTING DEVICE MATERIAL AND LIGHT-EMITTING DEVICE CRY1, MMS19, CRY2 ALOX5 1396/4885MAOB 2610/4885TNKS 1358/4885
US-20070247063-A1 Light-Emitting Device Material and Light-Emitting Device CRY1, CRY2, ATXN10 ALOX5 775/4885MAOB 2470/4885TNKS 2693/4885
US-20090066245-A1 MATERIAL FOR LIGHT-EMITTING ELEMENT AND LIGHT EMITTING ELEMENT PYM1, CRY1, S100A10 ALOX5 1264/4885MAOB 2180/4885TNKS 2936/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.