SCHEMBL9890844

SCHEMBL9890844

Cc1ccc(-c2c3ccc(-c4cccc5c4oc4ccccc45)cc3c(-c3ccc(C)cc3)c3ccc(-c4cccc5c4oc4ccccc45)cc23)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.57
MAOB P27338 2/20 0.46
PRKDC P78527 4/20 0.45
GGPS1 O95749 1/20 0.43
TNKS O95271 1/20 0.43
PARP1 P09874 1/20 0.43
TNKS2 Q9H2K2 1/20 0.43
PARP2 Q9UGN5 1/20 0.43
PTGES2 Q9H7Z7 1/20 0.40
LMNA P02545 1/20 0.38
TP53 P04637 1/20 0.38
RET P07949 1/20 0.38
TSHR P16473 1/20 0.38
ALOX12 P18054 1/20 0.38
KDR P35968 1/20 0.38
HTT P42858 1/20 0.38
PGR P06401 1/20 0.38
PTPRF P10586 1/20 0.36
PTPN2 P17706 1/20 0.36
PTPN1 P18031 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10442784 0.96 ALOX5 (0.53) ALOX5MAOBPRKDCGGPS1TNKS
SCHEMBL10442955 0.95 ALOX5 (0.52) ALOX5MAOBPRKDCGGPS1TNKS
SCHEMBL10443239 0.95 ALOX5 (0.52) ALOX5MAOBPRKDCGGPS1TNKS
SCHEMBL1687986 0.92 ALOX5 (0.55) ALOX5MAOBPRKDCGGPS1TNKS
SCHEMBL10442512 0.91 ALOX5 (0.51) ALOX5MAOBPRKDCGGPS1TNKS
SCHEMBL9890841 0.90 ALOX5 (0.61) ALOX5PRKDCGGPS1TNKSPARP1
SCHEMBL13556993 0.90 ALOX5 (0.61) ALOX5PRKDCGGPS1TNKSPARP1
SCHEMBL12577991 0.89 ALOX5 (0.59) ALOX5PRKDCGGPS1PTGES2LMNA
SCHEMBL9890832 0.89 ALOX5 (0.51) ALOX5MAOBPRKDCGGPS1TNKS
SCHEMBL896205 0.88 ALOX5 (0.58) ALOX5PRKDCGGPS1TNKSPARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8502201-B2 Light-emitting element TORAY INDUSTRIES, INC. (JP) 2013-08-06 US disclosed
US-8502201-B2 Light-emitting element TORAY INDUSTRIES, INC. (JP) 2013-08-06 US disclosed
US-20120138907-A1 LIGHT-EMITTING DEVICE MATERIAL AND LIGHT-EMITTING DEVICE TORAY INDUSTRIES, INC. (JP) 2012-06-07 US disclosed
US-20120138907-A1 LIGHT-EMITTING DEVICE MATERIAL AND LIGHT-EMITTING DEVICE TORAY INDUSTRIES, INC. (JP) 2012-06-07 US disclosed
US-8084146-B2 Light-emitting device material and light-emitting device TORAY INDUSTRIES, INC. (JP) 2011-12-27 US disclosed
US-8084146-B2 Light-emitting device material and light-emitting device TORAY INDUSTRIES, INC. (JP) 2011-12-27 US disclosed
US-20110121268-A1 LIGHT-EMITTING ELEMENT TORAY INDUSTRIES, INC. (JP) 2011-05-26 US disclosed
US-20110121268-A1 LIGHT-EMITTING ELEMENT TORAY INDUSTRIES, INC. (JP) 2011-05-26 US disclosed
US-7901794-B2 Material for light-emitting element and light emitting element TORAY INDUSTRIES, INC. (JP) 2011-03-08 US disclosed
US-7901794-B2 Material for light-emitting element and light emitting element TORAY INDUSTRIES, INC. (JP) 2011-03-08 US disclosed
US-20090066245-A1 MATERIAL FOR LIGHT-EMITTING ELEMENT AND LIGHT EMITTING ELEMENT TORAY INDUSTRIES, INC. (JP) 2009-03-12 US disclosed
US-20090066245-A1 MATERIAL FOR LIGHT-EMITTING ELEMENT AND LIGHT EMITTING ELEMENT TORAY INDUSTRIES, INC. (JP) 2009-03-12 US disclosed
US-20070247063-A1 Light-Emitting Device Material and Light-Emitting Device TORAY INDUSTRIES INC. (JP) 2007-10-25 US disclosed
US-20070247063-A1 Light-Emitting Device Material and Light-Emitting Device TORAY INDUSTRIES INC. (JP) 2007-10-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120138907-A1 LIGHT-EMITTING DEVICE MATERIAL AND LIGHT-EMITTING DEVICE CRY1, MMS19, CRY2 ALOX5 1396/4885MAOB 2610/4885PRKDC 4779/4885
US-20070247063-A1 Light-Emitting Device Material and Light-Emitting Device CRY1, CRY2, ATXN10 ALOX5 775/4885MAOB 2470/4885PRKDC 4739/4885
US-20090066245-A1 MATERIAL FOR LIGHT-EMITTING ELEMENT AND LIGHT EMITTING ELEMENT PYM1, CRY1, S100A10 ALOX5 1264/4885MAOB 2180/4885PRKDC 4832/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.