Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.50 |
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.46 |
| ▸ | EGFR | P00533 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | RAD52 | P43351 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.44 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9893975 | 1.00 | MAPT (0.50) | MAPTLMNAMDM2MAOASMN1; SMN2 | |
| SCHEMBL7122672 | 0.78 | MAPT (0.53) | MAPTLMNAMAOASMN1; SMN2MAPK1 | |
| SCHEMBL7129853 | 0.75 | MAPT (0.53) | MAPTLMNAMAOASMN1; SMN2MAPK1 | |
| SCHEMBL7311759 | 0.75 | LMNA (0.48) | MAPTLMNAMDM2SMN1; SMN2RAB9A | |
| SCHEMBL7311755 | 0.75 | LMNA (0.48) | MAPTLMNAMDM2SMN1; SMN2RAB9A | |
| SCHEMBL373158 | 0.75 | MAOA (0.49) | MAPTLMNAMAOASMN1; SMN2MAPK1 | |
| SCHEMBL5485262 | 0.74 | MAOA (0.48) | MAPTLMNAMAOASMN1; SMN2MAPK1 | |
| SCHEMBL5485260 | 0.74 | MAPT (0.49) | MAPTLMNAMAOASMN1; SMN2MAPK1 | |
| SCHEMBL9519629 | 0.74 | MAPT (0.54) | MAPTLMNAMDM2SMN1; SMN2MAPK1 | |
| SCHEMBL3631342 | 0.74 | MAPT (0.54) | MAPTLMNAMDM2SMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9017716-B2 | Ophthalmic lens | MENICON CO., LTD. (JP) | 2015-04-28 | — | — | US | disclosed |
| US-20120148519-A1 | OPHTHALMIC LENS | MENICON CO., LTD. (JP) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120148519-A1 | OPHTHALMIC LENS | AQP4, CRYAA, UACA | MAPT 851/4885LMNA 2854/4885MDM2 784/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.