Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 8/20 | 0.48 |
| ▸ | RAB9A | P51151 | 8/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.47 |
| ▸ | TRPC4 | Q9UBN4 | 1/20 | 0.47 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4873251 | 0.79 | ALDH1A1 (0.67) | ALDH1A1MAPK1HSD17B10LMNANPSR1 | |
| SCHEMBL30002927 | 0.79 | ALDH1A1 (0.67) | ALDH1A1MAPK1HSD17B10LMNANPSR1 | |
| SCHEMBL3997830 | 0.78 | NUDT1 (0.44) | KMT2A | |
| Carbendazim SCHEMBL5443295 | 0.75 | LMNA (0.64) | ALDH1A1HSD17B10LMNACYP3A4NPC1 | |
| SCHEMBL14009913 | 0.72 | ALDH1A1 (0.67) | ALDH1A1MAPK1HSD17B10LMNANPSR1 | |
| SCHEMBL27646560 | 0.72 | L3MBTL1 (0.49) | ALDH1A1MAPK1HSD17B10LMNANPSR1 | |
| SCHEMBL2016737 | 0.72 | LMNA (0.61) | ALDH1A1MAPK1HSD17B10LMNANPSR1 | |
| SCHEMBL29502497 | 0.72 | LMNA (0.61) | ALDH1A1MAPK1HSD17B10LMNANPSR1 | |
| SCHEMBL19538202 | 0.72 | RAB9A (0.56) | ALDH1A1MAPK1HSD17B10LMNANPSR1 | |
| Carbendazim SCHEMBL5440632 | 0.72 | LMNA (0.64) | ALDH1A1HSD17B10LMNACYP3A4NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7863310-B2 | Kinase inhibitors | ELI LILLY AND COMPANY (US) | 2011-01-04 | — | — | US | disclosed |