Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.38 |
| ▸ | CES1 | P23141 | 3/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.37 |
| ▸ | PPARG | P37231 | 7/20 | 0.37 |
| ▸ | PPARD | Q03181 | 7/20 | 0.37 |
| ▸ | PPARA | Q07869 | 7/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.37 |
| ▸ | TSHR | P16473 | 5/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TLR2 | O60603 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | FABP4 | P15090 | 2/20 | 0.37 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.37 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15305871 | 0.86 | CES2 (0.37) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL30205659 | 0.85 | LMNA (0.45) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL21049771 | 0.85 | LMNA (0.45) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL30205784 | 0.85 | LMNA (0.45) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL96679 | 0.85 | LMNA (0.45) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL30205650 | 0.85 | LMNA (0.45) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL21049772 | 0.85 | LMNA (0.45) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL97747 | 0.85 | LMNA (0.45) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL30205788 | 0.85 | LMNA (0.45) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL100262 | 0.85 | LMNA (0.45) | CES2CES1GPR84PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2379634-B1 | RUBBER COMPOUND CONTAINING A BLOCKED MERCAPTOSILANE COUPLING AGENT | MICHELIN & CIE (FR) | 2016-04-20 | — | — | EP | disclosed |
| US-9150595-B2 | Process for producing silane coupling agent | BRIDGESTONE CORPORATION (JP) | 2015-10-06 | — | — | US | disclosed |
| US-8957155-B2 | Blocked mercaptosilane coupling agent | COMPAGNIE GENERALE DES ETABLISSEMENTS (FR) | 2015-02-17 | — | — | US | disclosed |
| US-20150005448-A1 | RUBBER COMPOSITION COMPRISING A BLOCKED MERCAPTOSILANE COUPLING AGENT | MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) | 2015-01-01 | — | — | US | disclosed |
| US-8623937-B2 | Rubber compound containing a blocked mercaptosilane coupling agent | COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) | 2014-01-07 | — | — | US | disclosed |
| EP-2379568-B1 | BLOCKED MERCAPTOSILANE COUPLING AGENT | MICHELIN & CIE (FR) | 2013-08-14 | — | — | EP | disclosed |
| WO-2013087693-A1 | RUBBER COMPOSITION COMPRISING A BLOCKED MERCAPTOSILANE COUPLING AGENT | COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) | 2013-06-20 | — | — | WO | disclosed |
| US-20120149929-A1 | PROCESS FOR PRODUCING SILANE COUPLING AGENT | BRIDGESTONE CORPORATION (JP) | 2012-06-14 | — | — | US | disclosed |
| US-20110294953-A1 | BLOCKED MERCAPTOSILANE COUPLING AGENT | MICHELIN RECHERCHE ET TECHNIQUE S.A. | 2011-12-01 | — | — | US | disclosed |
| WO-2010072683-A1 | RUBBER COMPOUND CONTAINING A BLOCKED MERCAPTOSILANE COUPLING AGENT | SOCIETE DE TECHNOLOGIE MICHELIN (FR) | 2010-07-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110294953-A1 | BLOCKED MERCAPTOSILANE COUPLING AGENT | CCR1, CCR2, SAV1 | CES2 2870/4885CES1 3011/4885GPR84 855/4885 |
| US-20120149929-A1 | PROCESS FOR PRODUCING SILANE COUPLING AGENT | HAO2, SAMM50, SKP2 | CES2 3262/4885CES1 4636/4885GPR84 3366/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.