Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.66 |
| ▸ | TSHR | P16473 | 3/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.66 |
| ▸ | F2 | P00734 | 3/20 | 0.60 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.60 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.60 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.60 |
| ▸ | NPC1 | O15118 | 7/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.59 |
| ▸ | RAB9A | P51151 | 6/20 | 0.59 |
| ▸ | MEN1 | O00255 | 5/20 | 0.59 |
| ▸ | POLB | P06746 | 4/20 | 0.59 |
| ▸ | CA12 | O43570 | 2/20 | 0.59 |
| ▸ | CA2 | P00918 | 2/20 | 0.59 |
| ▸ | CA9 | Q16790 | 2/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | MYC | P01106 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14613041 | 0.85 | ALDH1A1 (0.72) | ALDH1A1TSHRMAPK1TDP1HSD17B10 | |
| SCHEMBL11123288 | 0.82 | S100A4 (0.57) | ALDH1A1TDP1F2PRSS1PRSS2 | |
| SCHEMBL11123296 | 0.82 | S100A4 (0.57) | ALDH1A1TDP1F2PRSS1PRSS2 | |
| SCHEMBL11123293 | 0.82 | S100A4 (0.57) | ALDH1A1TDP1F2PRSS1PRSS2 | |
| Methyl Yellow SCHEMBL7720573 | 0.82 | ALDH1A1 (0.78) | ALDH1A1TSHRMAPK1TDP1HSD17B10 | |
| Dimethyl Yellow SCHEMBL7720567 | 0.82 | ALDH1A1 (0.78) | ALDH1A1TSHRMAPK1TDP1HSD17B10 | |
| Methyl Yellow SCHEMBL239712 | 0.81 | ALDH1A1 (1.00) | ALDH1A1TSHRMAPK1TDP1HSD17B10 | |
| SCHEMBL8982830 | 0.81 | ALDH1A1 (1.00) | ALDH1A1TSHRMAPK1TDP1HSD17B10 | |
| SCHEMBL10909165 | 0.81 | ALDH1A1 (1.00) | ALDH1A1TSHRMAPK1TDP1HSD17B10 | |
| SCHEMBL8982839 | 0.81 | ALDH1A1 (1.00) | ALDH1A1TSHRMAPK1TDP1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120178086-A1 | REDUCTIVE RELEASE PROBES CONTAINING A CHEMOSELECTIVELY CLEAVABLE ALPHA-AZIDOETHER LINKER AND METHODS OF USE THEREOF | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2012-07-12 | — | — | US | claimed |
| WO-2011005821-A1 | REDUCTIVE RELEASE PROBES CONTAINING A CHEMOSELECTIVELY CLEAVABLE ALPHA-AZIDOETHER LINKER AND METHODS OF USE THEREOF | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2011-01-13 | — | — | WO | claimed |
| US-7745614-B2 | Universal linker compositions for the release or transfer of chemical agents from a polynucleotide | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2010-06-29 | — | — | US | claimed |
| US-20060199192-A1 | Universal linker compositions for the release or transfer of chemical agents from a polynucleotide | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2006-09-07 | — | — | US | claimed |
| US-9422232-B2 | Reductive release probes containing a chemoselectively cleavable α-azidoether linker and methods of use thereof | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2016-08-23 | — | — | US | disclosed |
| US-9416155-B2 | Direct sensing of molecular species by polyfluors on a DNA backbone | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2016-08-16 | — | — | US | disclosed |
| US-20120309107-A1 | Direct Sensing of Molecular Species by Polyfluors on a DNA Backbone | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2012-12-06 | — | — | US | disclosed |
| US-20120178086-A1 | REDUCTIVE RELEASE PROBES CONTAINING A CHEMOSELECTIVELY CLEAVABLE ALPHA-AZIDOETHER LINKER AND METHODS OF USE THEREOF | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2012-07-12 | — | — | US | disclosed |
| WO-2011097437-A1 | DOUBLE DISPLACEMENT PROBES FOR NUCLEIC ACID DETECTION | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2011-08-11 | — | — | WO | disclosed |
| WO-2011081939-A1 | DIRECT SENSING OF MOLECULAR SPECIES BY POLYFLUORS ON A DNA BACKBONE | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2011-07-07 | — | — | WO | disclosed |
| WO-2011005821-A1 | REDUCTIVE RELEASE PROBES CONTAINING A CHEMOSELECTIVELY CLEAVABLE ALPHA-AZIDOETHER LINKER AND METHODS OF USE THEREOF | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2011-01-13 | — | — | WO | disclosed |
| US-7745614-B2 | Universal linker compositions for the release or transfer of chemical agents from a polynucleotide | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2010-06-29 | — | — | US | disclosed |
| US-20060199192-A1 | Universal linker compositions for the release or transfer of chemical agents from a polynucleotide | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2006-09-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120309107-A1 | Direct Sensing of Molecular Species by Polyfluors on a DNA Backbone | ERCC4, POLL, POLQ | ALDH1A1 3769/4885TSHR 2544/4885MAPK1 4054/4885 |
| US-20060199192-A1 | Universal linker compositions for the release or transfer of chemical agents from a polynucleotide | ADAR, POLRMT, RNGTT | ALDH1A1 2876/4885TSHR 988/4885MAPK1 2218/4885 |
| US-20120178086-A1 | REDUCTIVE RELEASE PROBES CONTAINING A CHEMOSELECTIVELY CLEAVABLE ALPHA-AZIDOETHER LINKER AND METHODS OF USE THEREOF | CPSF1, CPSF7, CPSF6 | ALDH1A1 2568/4885TSHR 600/4885MAPK1 3593/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.