Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 3/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CETP | P11597 | 3/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9900009 | 1.00 | ALDH1A1 (0.46) | ALDH1A1CES2CES1L3MBTL1CYP3A4 | |
| SCHEMBL9898660 | 0.87 | ALDH1A1 (0.49) | ALDH1A1CES2CES1L3MBTL1PPARG | |
| SCHEMBL9898661 | 0.87 | ALDH1A1 (0.49) | ALDH1A1CES2CES1L3MBTL1PPARG | |
| SCHEMBL10231752 | 0.83 | CES2 (0.44) | ALDH1A1CES2CES1L3MBTL1CYP3A4 | |
| SCHEMBL2044090 | 0.83 | L3MBTL1 (0.44) | ALDH1A1L3MBTL1CYP3A4CYP2C19PPARG | |
| SCHEMBL2044089 | 0.83 | L3MBTL1 (0.44) | ALDH1A1L3MBTL1CYP3A4CYP2C19PPARG | |
| SCHEMBL934853 | 0.82 | ALOX5 (0.56) | ALDH1A1L3MBTL1PPARGPPARAALOX5 | |
| SCHEMBL934854 | 0.82 | ALOX5 (0.56) | ALDH1A1L3MBTL1PPARGPPARAALOX5 | |
| SCHEMBL9900542 | 0.82 | ALDH1A1 (0.53) | ALDH1A1L3MBTL1PPARGPPARAALOX5 | |
| SCHEMBL1629179 | 0.82 | ALDH1A1 (0.53) | ALDH1A1L3MBTL1PPARGPPARAALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8748531-B2 | Polymers functionalized with oxime compounds containing an acyl group | BRIDGESTONE CORPORATION (JP) | 2014-06-10 | — | — | US | claimed |
| EP-2649102-A1 | POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP | Bridgestone Corporation (JP) | 2013-10-16 | — | — | EP | claimed |
| US-20120149833-A1 | POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP | BRIDGESTONE CORPORATION (JP) | 2012-06-14 | — | — | US | claimed |
| WO-2012078962-A1 | POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP | BRIDGESTONE CORPORATION (JP) | 2012-06-14 | — | — | WO | claimed |
| US-8748531-B2 | Polymers functionalized with oxime compounds containing an acyl group | BRIDGESTONE CORPORATION (JP) | 2014-06-10 | — | — | US | disclosed |
| US-20120149833-A1 | POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP | BRIDGESTONE CORPORATION (JP) | 2012-06-14 | — | — | US | disclosed |