Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 2/20 | 0.37 |
| ▸ | NOS1 | P29475 | 2/20 | 0.37 |
| ▸ | NOS2 | P35228 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.30 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.30 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.30 |
| ▸ | EBP | Q15125 | 1/20 | 0.30 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9901797 | 0.85 | HTR3E (0.41) | NOS3NOS1NOS2GAAKMT2A | |
| SCHEMBL9902748 | 0.80 | GRIN2D (0.42) | NOS1GAASIGMAR1L3MBTL1GRIN2D | |
| SCHEMBL9902512 | 0.80 | SIGMAR1 (0.42) | NOS1SIGMAR1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL9901424 | 0.75 | NOS1 (0.41) | NOS3NOS1NOS2GAASIGMAR1 | |
| SCHEMBL9901710 | 0.75 | ALDH1A1 (0.40) | NOS3NOS1NOS2GAAKMT2A | |
| SCHEMBL9903487 | 0.74 | KMT2A (0.45) | NOS3NOS1NOS2GAAKMT2A | |
| SCHEMBL9901901 | 0.74 | SIGMAR1 (0.36) | NOS1KDM4ESIGMAR1L3MBTL1GRIN2D | |
| SCHEMBL9902718 | 0.73 | KDM4E (0.30) | GAAKMT2AKDM4E | |
| SCHEMBL9901448 | 0.72 | HTR3E (0.38) | GAAKMT2AKDM4ESIGMAR1L3MBTL1 | |
| SCHEMBL9901584 | 0.72 | HCRTR2 (0.35) | GAAKMT2AKDM4EL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2649048-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | Radikal Therapeutics Inc. (US) | 2013-10-16 | — | — | EP | disclosed |
| WO-2012077108-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | RADIKAL THERAPEUTICS INC. (US) | 2012-06-14 | — | — | WO | disclosed |