Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9902476 | 0.86 | KDM4E (0.40) | KDM4EGAAKMT2A | |
| SCHEMBL9902286 | 0.81 | KDM4E (0.35) | KDM4EGAAKMT2A | |
| SCHEMBL9901901 | 0.78 | SIGMAR1 (0.36) | KDM4E | |
| SCHEMBL9905760 | 0.77 | ADRA2A (0.33) | KDM4EGAAKMT2A | |
| SCHEMBL9901424 | 0.77 | NOS1 (0.41) | GAA | |
| SCHEMBL9902512 | 0.74 | SIGMAR1 (0.42) | — | |
| SCHEMBL9903487 | 0.74 | KMT2A (0.45) | KDM4EGAAKMT2A | |
| SCHEMBL9902713 | 0.74 | GRM5 (0.33) | KDM4EGAAKMT2A | |
| SCHEMBL9901797 | 0.73 | HTR3E (0.41) | KDM4EGAAKMT2A | |
| SCHEMBL9901586 | 0.73 | NOS3 (0.37) | KDM4EGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2649048-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | Radikal Therapeutics Inc. (US) | 2013-10-16 | — | — | EP | disclosed |
| WO-2012077108-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | RADIKAL THERAPEUTICS INC. (US) | 2012-06-14 | — | — | WO | disclosed |