Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMARCA2 | P51531 | 9/20 | 0.39 |
| ▸ | SMARCA4 | P51532 | 8/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.34 |
| ▸ | GRM5 | P41594 | 3/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.30 |
| ▸ | PI4KA | P42356 | 1/20 | 0.30 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.30 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.30 |
| ▸ | PIK3R4 | Q99570 | 1/20 | 0.30 |
| ▸ | PIP5K1A | Q99755 | 1/20 | 0.30 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.30 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.30 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9901787 | 0.83 | GAA (0.43) | KDM4EGAAKMT2A | |
| SCHEMBL9902706 | 0.83 | KCNQ3 (0.35) | KDM4EGAAKMT2A | |
| SCHEMBL9903481 | 0.81 | KMT2A (0.38) | KMT2A | |
| SCHEMBL9902043 | 0.81 | KDM4E (0.39) | SMARCA2SMARCA4KDM4EGAAKMT2A | |
| SCHEMBL9901445 | 0.81 | EPHX2 (0.33) | GAAKMT2A | |
| SCHEMBL9901704 | 0.81 | EPHX2 (0.36) | GAA | |
| SCHEMBL9901577 | 0.78 | GAA (0.34) | KDM4EGAAKMT2A | |
| SCHEMBL9902509 | 0.77 | GAA (0.37) | KDM4EGAAKMT2AGRM5 | |
| SCHEMBL9901900 | 0.77 | EPHX2 (0.40) | GAAKMT2A | |
| SCHEMBL9901676 | 0.77 | TSHR (0.40) | KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2649048-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | Radikal Therapeutics Inc. (US) | 2013-10-16 | — | — | EP | disclosed |
| WO-2012077108-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | RADIKAL THERAPEUTICS INC. (US) | 2012-06-14 | — | — | WO | disclosed |