Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.38 |
| ▸ | MEN1 | O00255 | 6/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.37 |
| ▸ | HTR3B | O95264 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9901445 | 0.88 | EPHX2 (0.33) | KMT2AMEN1LMNAALDH1A1MAPT | |
| SCHEMBL9902509 | 0.86 | GAA (0.37) | KMT2AMEN1LMNAALDH1A1HTT | |
| SCHEMBL9901900 | 0.86 | EPHX2 (0.40) | KMT2AMEN1ALDH1A1EPHX2NPC1 | |
| SCHEMBL9901704 | 0.85 | EPHX2 (0.36) | LMNAALDH1A1MAPTHTTEPHX2 | |
| SCHEMBL9901577 | 0.85 | GAA (0.34) | KMT2ALMNAALDH1A1MAPTTSHR | |
| SCHEMBL9901779 | 0.81 | SMARCA2 (0.39) | KMT2A | |
| SCHEMBL9901676 | 0.79 | TSHR (0.40) | KMT2AMEN1LMNAALDH1A1HTT | |
| SCHEMBL9901795 | 0.78 | P2RX7 (0.36) | KMT2AMEN1LMNAALDH1A1EPHX2 | |
| SCHEMBL9902706 | 0.78 | KCNQ3 (0.35) | KMT2A | |
| SCHEMBL9901421 | 0.78 | EPHX2 (0.36) | KMT2AALDH1A1MAPTHTTEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2649048-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | Radikal Therapeutics Inc. (US) | 2013-10-16 | — | — | EP | disclosed |
| WO-2012077108-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | RADIKAL THERAPEUTICS INC. (US) | 2012-06-14 | — | — | WO | disclosed |