Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9901787 | 0.85 | GAA (0.43) | TSHREPHX2KMT2AALDH1A1CYP3A4 | |
| SCHEMBL9901577 | 0.85 | GAA (0.34) | TSHREPHX2KMT2AALDH1A1POLB | |
| SCHEMBL16994485 | 0.80 | P2RX7 (0.43) | TSHREPHX2MEN1USP2KMT2A | |
| SCHEMBL19668355 | 0.80 | P2RX7 (0.43) | TSHREPHX2MEN1USP2KMT2A | |
| SCHEMBL9905759 | 0.80 | KCNQ3 (0.33) | KMT2AKDM4E | |
| SCHEMBL9902706 | 0.80 | KCNQ3 (0.35) | KMT2AKDM4E | |
| SCHEMBL9901900 | 0.79 | EPHX2 (0.40) | EPHX2MEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL9902509 | 0.79 | GAA (0.37) | MEN1KMT2AALDH1A1KDM4EHTT | |
| SCHEMBL9903481 | 0.79 | KMT2A (0.38) | TSHREPHX2MEN1KMT2AALDH1A1 | |
| SCHEMBL9902746 | 0.78 | OPRM1 (0.37) | EPHX2MEN1KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2649048-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | Radikal Therapeutics Inc. (US) | 2013-10-16 | — | — | EP | disclosed |
| WO-2012077108-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | RADIKAL THERAPEUTICS INC. (US) | 2012-06-14 | — | — | WO | disclosed |