Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9902509 | 0.86 | GAA (0.37) | ALDH1A1RAB9AMEN1KMT2AGAA | |
| SCHEMBL9903481 | 0.86 | KMT2A (0.38) | EPHX2ALDH1A1CYP2D6NPC1RAB9A | |
| SCHEMBL9901421 | 0.85 | EPHX2 (0.36) | EPHX2ALDH1A1SIGMAR1NPC1RAB9A | |
| SCHEMBL9901577 | 0.85 | GAA (0.34) | EPHX2ALDH1A1KMT2AGAASMN1; SMN2 | |
| SCHEMBL16994514 | 0.80 | P2RX7 (0.43) | EPHX2ALDH1A1CYP2D6SIGMAR1NPC1 | |
| SCHEMBL9901676 | 0.79 | TSHR (0.40) | EPHX2ALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL9905759 | 0.78 | KCNQ3 (0.33) | KMT2AGAA | |
| SCHEMBL9902713 | 0.78 | GRM5 (0.33) | KMT2AGAA | |
| SCHEMBL9901445 | 0.78 | EPHX2 (0.33) | EPHX2ALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL9902746 | 0.78 | OPRM1 (0.37) | EPHX2ALDH1A1NPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2649048-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | Radikal Therapeutics Inc. (US) | 2013-10-16 | — | — | EP | disclosed |
| WO-2012077108-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | RADIKAL THERAPEUTICS INC. (US) | 2012-06-14 | — | — | WO | disclosed |