Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | IDH1 | O75874 | 2/20 | 0.38 |
| ▸ | IDH2 | P48735 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.34 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.33 |
| ▸ | TNF | P01375 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.32 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29705749 | 1.00 | MAPT (0.43) | MAPTMEN1KMT2AL3MBTL1IDH1 | |
| SCHEMBL1426671 | 0.84 | MEN1 (0.50) | MAPTMEN1KMT2AKDM4ETDP1 | |
| SCHEMBL2940122 | 0.79 | MEN1 (0.43) | MAPTMEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL29056051 | 0.75 | MEN1 (0.43) | MAPTMEN1KMT2AKDM4ETDP1 | |
| SCHEMBL1025377 | 0.75 | IRAK4 (0.48) | MAPTMEN1KMT2ACYP3A4KDM4E | |
| SCHEMBL24890395 | 0.75 | MEN1 (0.43) | MAPTMEN1KMT2AKDM4ETDP1 | |
| SCHEMBL28889311 | 0.75 | MEN1 (0.43) | MAPTMEN1KMT2AKDM4ETDP1 | |
| SCHEMBL1249349 | 0.75 | MEN1 (0.43) | MAPTMEN1KMT2AKDM4ETDP1 | |
| SCHEMBL22071098 | 0.75 | MEN1 (0.43) | MAPTMEN1KMT2AKDM4ETDP1 | |
| SCHEMBL30395089 | 0.75 | IRAK4 (0.48) | MAPTMEN1KMT2ACYP3A4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4737449-A1 | P53-Y220C SELECTIVE SMALL-MOLECULAR REACTIVATOR COMPOUND, PHARMACEUTICAL COMPOSITION AND USE THEREOF | Changchun Genescience Pharmaceutical Co., Ltd. (CN) | 2026-05-06 | — | — | EP | disclosed |
| WO-2025002177-A1 | P53-Y220C SELECTIVE SMALL-MOLECULAR REACTIVATOR COMPOUND, PHARMACEUTICAL COMPOSITION AND USE THEREOF | 长春金赛药业有限责任公司 | 2025-01-02 | — | — | WO | disclosed |
| CN-117986235-A | P53-Y220C selective small molecule reactivation agent compound, pharmaceutical composition and application thereof | 长春金赛药业有限责任公司 | 2024-05-07 | — | — | CN | disclosed |
| US-20230046018-A1 | BIARYL COMPOUND AS PAN-RAF KINASE INHIBITOR | QILU PHARMACEUTICAL CO., LTD. (CN) | 2023-02-16 | — | — | US | disclosed |
| WO-2022253334-A1 | CRYSTAL FORM OF RAF KINASE INHIBITOR AND PREPARATION METHOD THEREFOR | 南京明德新药研发有限公司 | 2022-12-08 | — | — | WO | disclosed |
| CN-114555573-A | Prostaglandin E2(PGE2)EP4Receptor antagonists | 多曼治疗学公司 | 2022-05-27 | — | — | CN | disclosed |
| WO-2021110141-A1 | BIARYL COMPOUND AS PAN-RAF KINASE INHIBITOR | 南京明德新药研发有限公司 | 2021-06-10 | — | — | WO | disclosed |
| US-20160159773-A1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2016-06-09 | — | — | US | disclosed |
| US-20160159773-A1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2016-06-09 | — | — | US | disclosed |
| US-20160031812-A1 | SEPIAPTERIN REDUCTASE INHIBITORS FOR THE TREATMENT OF PAIN | SOLACE PHARMACEUTICALS UK LTD. (GB) | 2016-02-04 | — | — | US | disclosed |
| CN-101400660-A | Triazole derivative or salt thereof | ASTELLAS PHARMA INC (JP) | 2009-04-01 | — | — | CN | disclosed |
| US-20090082367-A1 | TRIAZOLE DERIVATIVE OR A SALT THEREOF | ASTELLAS PHARMA INC. (JP) | 2009-03-26 | — | — | US | disclosed |
| EP-1995243-A1 | TRIAZOLE DERIVATIVE OR SALT THEREOF | Astellas Pharma Inc. (JP) | 2008-11-26 | — | — | EP | disclosed |
| WO-2004108722-A1 | ORTHOCONDENSED POLYCYCLIC AMINOPYRROLE DERIVATIVES COMPRISING AN ELECTRO-ATTRACTIVE SUBSTITUENT, COMBINATION PRODUCTS OF SAID DERIVATIVES, AND METHOD FOR THE PRODUCTION THEREOF | PIERRE FABRE UROLOGIE (FR) | 2004-12-16 | — | — | WO | disclosed |
| WO-2001017965-A2 | CYANOPIPERIDINES AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2001-03-15 | — | — | WO | disclosed |
| US-5677329-A | ANTAGONIST TO EPIDERMAL GROWTH FACTOR | RHONE-POULENC RORER PHARMACEUTICALS, INC. (US) | 1997-10-14 | — | — | US | disclosed |
| US-5597837-A | Method and composition for treating psoriasis with styryl-substituted pyridyl compounds | Rh one-Poulenc Rorer Pharmaceuticals Inc. (US) | 1997-01-28 | — | — | US | disclosed |
| EP-0525109-A4 | STYRYL-SUBSTITUTED MONOCYCLIC AND BICYCLIC HETEROARYL COMPOUNDS WHICH INHIBIT EGF RECEPTOR TYROSINE KINASE | — | 1993-06-30 | — | — | EP | disclosed |
| EP-0525109-A1 | STYRYL-SUBSTITUTED MONOCYCLIC AND BICYCLIC HETEROARYL COMPOUNDS WHICH INHIBIT EGF RECEPTOR TYROSINE KINASE | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1993-02-03 | — | — | EP | disclosed |
| US-4369322-A | WITH CYANOGEN CHLORIDE | DEGUSSA AG (DE) | 1983-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160031812-A1 | SEPIAPTERIN REDUCTASE INHIBITORS FOR THE TREATMENT OF PAIN | SPR, QDPR, SRR | MAPT 2193/4885MEN1 4856/4885KMT2A 3756/4885 |
| US-20230046018-A1 | BIARYL COMPOUND AS PAN-RAF KINASE INHIBITOR | BRAF, RAF1, ARAF | MAPT 3593/4885MEN1 2574/4885KMT2A 751/4885 |
| US-20160159773-A1 | HETEROCYCLIC COMPOUND | TYK2, SSB, UACA | MAPT 277/4885MEN1 1167/4885KMT2A 281/4885 |
| US-20090082367-A1 | TRIAZOLE DERIVATIVE OR A SALT THEREOF | HSD11B1, HSD11B2, HSD17B1 | MAPT 3869/4885MEN1 2335/4885KMT2A 1938/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.