Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.38 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.36 |
| ▸ | PKN2 | Q16513 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | RPS6KA5 | O75582 | 2/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.36 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CHUK | O15111 | 1/20 | 0.36 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9901790 | 0.84 | GAA (0.40) | KDM4EGAAALOX15ALDH1A1NTRK3 | |
| SCHEMBL9902971 | 0.74 | ROCK2 (0.36) | GAAALOX15ALDH1A1ROCK2ROCK1 | |
| SCHEMBL9903243 | 0.71 | KDM4E (0.58) | KDM4EGAAALOX15ALDH1A1NTRK3 | |
| SCHEMBL9901580 | 0.70 | SIGMAR1 (0.40) | GAAALDH1A1TP53CYP3A4CYP2D6 | |
| SCHEMBL9901681 | 0.70 | KMT2A (0.39) | KDM4EALDH1A1TP53CYP3A4HTT | |
| SCHEMBL16994518 | 0.69 | KDM4E (0.51) | KDM4EGAAALOX15ALDH1A1NTRK3 | |
| SCHEMBL9901787 | 0.67 | GAA (0.43) | KDM4EGAAALOX15ALDH1A1NTRK3 | |
| SCHEMBL16994495 | 0.65 | KDM4E (0.44) | KDM4EGAAALOX15ALDH1A1CYP3A4 | |
| SCHEMBL17271384 | 0.65 | KDM4E (0.44) | KDM4EGAAALOX15ALDH1A1CYP3A4 | |
| SCHEMBL9905806 | 0.64 | P2RX7 (0.39) | KDM4EGAAALOX15ALDH1A1NTRK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2649048-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | Radikal Therapeutics Inc. (US) | 2013-10-16 | — | — | EP | disclosed |
| WO-2012077108-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | RADIKAL THERAPEUTICS INC. (US) | 2012-06-14 | — | — | WO | disclosed |