Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.32 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14214192 | 0.94 | ALDH1A1 (0.34) | CHRM4SMN1; SMN2CTSLLMNAMAPT | |
| SCHEMBL9905158 | 0.91 | CYP2C9 (0.34) | CHRM4SMN1; SMN2CTSLLMNAMAPT | |
| SCHEMBL9905325 | 0.90 | SIGMAR1 (0.35) | CHRM4SMN1; SMN2CTSLLMNAALDH1A1 | |
| SCHEMBL9921564 | 0.87 | TLR2 (0.35) | CHRM4MAPTL3MBTL1ALDH1A1HPGD | |
| SCHEMBL14122411 | 0.86 | CHRM4 (0.33) | CHRM4CTSLLMNAMAPTL3MBTL1 | |
| SCHEMBL9905376 | 0.84 | OPRM1 (0.35) | SMN1; SMN2MAPTALDH1A1HPGDCNR2 | |
| SCHEMBL14214197 | 0.83 | ALDH1A1 (0.34) | CHRM4SMN1; SMN2CTSLLMNAMAPT | |
| SCHEMBL9905381 | 0.83 | CTSL (0.39) | CHRM4SMN1; SMN2CTSLALDH1A1HPGD | |
| SCHEMBL9921566 | 0.80 | CYP2C9 (0.34) | CNR2 | |
| SCHEMBL64360 | 0.78 | CYP2C9 (0.40) | CHRM4SMN1; SMN2LMNAMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2649074-A1 | HIV INTEGRASE INHIBITORS | Bristol-Myers Squibb Company (US) | 2013-10-16 | — | — | EP | disclosed |
| WO-2012078844-A1 | HIV INTEGRASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-06-14 | — | — | WO | disclosed |