Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.39 |
| ▸ | GPR34 | Q9UPC5 | 2/20 | 0.34 |
| ▸ | YAP1 | P46937 | 1/20 | 0.34 |
| ▸ | CTSC | P53634 | 7/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | FAP | Q12884 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16130153 | 0.94 | CTSL (0.38) | CTSLGPR34YAP1CTSCCTSS | |
| SCHEMBL16130199 | 0.88 | CTSL (0.36) | CTSLYAP1CTSSCTSK | |
| SCHEMBL14122652 | 0.87 | CTSL (0.36) | CTSLGPR34YAP1CTSCCTSS | |
| SCHEMBL9905325 | 0.84 | SIGMAR1 (0.35) | CTSLCHRM4ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL9905089 | 0.83 | CHRM4 (0.34) | CTSLCHRM4ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL9905376 | 0.82 | OPRM1 (0.35) | ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL1669098 | 0.79 | CTSL (0.37) | CTSLGPR34YAP1CTSCCTSS | |
| SCHEMBL14214197 | 0.78 | ALDH1A1 (0.34) | CTSLYAP1CHRM4ALDH1A1HPGD | |
| SCHEMBL14214192 | 0.77 | ALDH1A1 (0.34) | CTSLCTSSCHRM4ALDH1A1HPGD | |
| SCHEMBL9905364 | 0.76 | MAPT (0.35) | ALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2649074-A1 | HIV INTEGRASE INHIBITORS | Bristol-Myers Squibb Company (US) | 2013-10-16 | — | — | EP | disclosed |
| WO-2012078844-A1 | HIV INTEGRASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-06-14 | — | — | WO | disclosed |