Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 4/20 | 0.35 |
| ▸ | CNR2 | P34972 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.31 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14214193 | 0.92 | TSHR (0.36) | OPRM1OPRD1OPRK1OGFRL1FAAH | |
| SCHEMBL9905325 | 0.85 | SIGMAR1 (0.35) | CNR2ALDH1A1HPGDKDM4ESMN1; SMN2 | |
| SCHEMBL9921626 | 0.84 | TLR2 (0.36) | OPRD1OPRK1MAPTALDH1A1 | |
| SCHEMBL9905089 | 0.84 | CHRM4 (0.34) | CNR2MAPTALDH1A1CNR1KMT2A | |
| SCHEMBL9905103 | 0.84 | RORC (0.36) | FAAHCNR2ALDH1A1GAA | |
| SCHEMBL14122239 | 0.83 | MAPT (0.33) | OPRM1OPRD1OPRK1OGFRL1FAAH | |
| SCHEMBL9905086 | 0.82 | HPGD (0.39) | MAPTHPGDKDM4ESMN1; SMN2 | |
| SCHEMBL9905381 | 0.82 | CTSL (0.39) | ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL14214197 | 0.79 | ALDH1A1 (0.34) | CNR2MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL14214192 | 0.78 | ALDH1A1 (0.34) | CNR2MAPTALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2649074-A1 | HIV INTEGRASE INHIBITORS | Bristol-Myers Squibb Company (US) | 2013-10-16 | — | — | EP | disclosed |
| WO-2012078844-A1 | HIV INTEGRASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-06-14 | — | — | WO | disclosed |