SCHEMBL9905226

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL143175	0.72	ALDH1A1 (0.54)	NOTUMF10DDB1CRBNSMN1; SMN2
	SCHEMBL19370804	0.72	MEN1 (0.51)	NOTUMCA12CA1CA2CA9
	SCHEMBL2222230	0.71	MGLL (0.50)	NOTUMF10SLC6A2SLC6A4SLC6A3
	SCHEMBL4243521	0.71	ALDH1A1 (0.59)	L3MBTL1F10SMN1; SMN2BRD4BRPF1
	SCHEMBL13907449	0.69	KMT2A (0.53)	F10SMN1; SMN2CA1CA2
	SCHEMBL6535778	0.69	HSP90AA1 (0.52)	L3MBTL1
	SCHEMBL18050030	0.69	FGFR1 (0.47)	L3MBTL1SMN1; SMN2CA12CA2CA9
	SCHEMBL13672252	0.69	FAAH (0.52)	L3MBTL1
	Amphenidone SCHEMBL586236	0.69	MAPT (0.57)	DDB1CRBNSLC6A2SLC6A4SLC6A3
	SCHEMBL31333639	0.69	MGLL (0.52)	L3MBTL1F10SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.