Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 3/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9902710 | 0.86 | ADRA2A (0.45) | ADRA2AADRA2BADRA2CKDM4EGAA | |
| SCHEMBL9902809 | 0.86 | KDM4E (0.40) | ADRA2AADRA2BADRA2CBACE1KDM4E | |
| SCHEMBL9901424 | 0.84 | NOS1 (0.41) | GAA | |
| SCHEMBL9901736 | 0.81 | KDM4E (0.35) | ADRA2AADRA2BADRA2CKDM4EGAA | |
| SCHEMBL9902748 | 0.80 | GRIN2D (0.42) | GAA | |
| SCHEMBL9901710 | 0.80 | ALDH1A1 (0.40) | KDM4EGAAKMT2A | |
| SCHEMBL9901901 | 0.78 | SIGMAR1 (0.36) | KDM4E | |
| SCHEMBL9902718 | 0.77 | KDM4E (0.30) | KDM4EGAAKMT2A | |
| SCHEMBL9901448 | 0.77 | HTR3E (0.38) | KDM4EGAAKMT2A | |
| SCHEMBL9901780 | 0.76 | KDM4E (0.34) | KDM4EGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2649048-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | Radikal Therapeutics Inc. (US) | 2013-10-16 | — | — | EP | disclosed |
| WO-2012077108-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | RADIKAL THERAPEUTICS INC. (US) | 2012-06-14 | — | — | WO | disclosed |