Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | LTA4H | P09960 | 3/20 | 0.52 |
| ▸ | CA12 | O43570 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | CA9 | Q16790 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.50 |
| ▸ | PTGES | O14684 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8530623 | 0.98 | RAB9A (0.53) | RAB9ANPC1LTA4HCA12CA1 | |
| Bromide SCHEMBL20984169 | 0.98 | RAB9A (0.53) | RAB9ANPC1LTA4HCA12CA1 | |
| SCHEMBL10958660 | 0.94 | NR5A1 (0.59) | RAB9ANPC1LTA4HTSHRNR5A1 | |
| Hydrochloric Acid SCHEMBL9636169 | 0.94 | NPC1 (0.58) | RAB9ANPC1LTA4HNR5A1GAA | |
| SCHEMBL7404276 | 0.92 | CA12 (0.52) | RAB9ANPC1LTA4HCA12CA1 | |
| Bromide SCHEMBL20984358 | 0.90 | CA12 (0.50) | RAB9ANPC1LTA4HCA12CA1 | |
| Hydrochloric Acid SCHEMBL4376159 | 0.90 | CA12 (0.50) | RAB9ANPC1LTA4HCA12CA1 | |
| Phosphoric Acid SCHEMBL20984592 | 0.89 | S1PR1 (0.50) | RAB9ANPC1CA12CA1CA2 | |
| Oxalic Acid SCHEMBL20984655 | 0.89 | GAA (0.54) | CA12CA1CA2CA9TSHR | |
| Sulfuric Acid SCHEMBL20984298 | 0.89 | NPC1 (0.58) | RAB9ANPC1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11040938-B2 | Continuous flow process for the synthesis of phenylhydrazine salts and substituted phenylhydrazine salts | SHANGHAI HYBRID-CHEM TECHNOLOGIES (CN) | 2021-06-22 | — | — | US | disclosed |
| US-20190152896-A1 | Continuous Flow Process For the Synthesis of Phenylhydrazine Salts and Substituted Phenylhydrazine Salts | SHANGHAI HYBRID-CHEM TECHNOLOGIES (CN) | 2019-05-23 | — | — | US | disclosed |
| CN-107663161-A | A kind of continuous stream synthesis technique of phenylhydrazine salt and substituted benzene hydrazonium salt | 上海惠和化德生物科技有限公司 | 2018-02-06 | — | — | CN | disclosed |
| US-9850183-B2 | Conjugates derived from non-steroidal anti-inflammatory drugs and methods of use thereof in imaging | Reiley Pharmaceuticals, Inc. (US) | 2017-12-26 | — | — | US | disclosed |
| US-9840515-B2 | Protein kinase D inhibitors | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2017-12-12 | — | — | US | disclosed |
| US-9751835-B2 | Processes and intermediates for preparing indole pharmaceuticals | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2017-09-05 | — | — | US | disclosed |
| US-20160107991-A1 | PROCESSES AND INTERMEDIATES FOR PREPARING INDOLE PHARMACEUTICALS | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION | 2016-04-21 | — | — | US | disclosed |
| US-20150374858-A1 | CONJUGATES DERIVED FROM NON-STEROIDAL ANTI-INFLAMMATORY DRUGS AND METHODS OF USE THEREOF IN IMAGING | Reiley Pharmaceuticals, Inc. | 2015-12-31 | — | — | US | disclosed |
| US-20150011759-A1 | PROCESSES FOR PREPARING (R)-2-METHYLPYRROLIDINE AND (S)-2-METHYLPYRROLIDINE AND TARTRATE SALTS THEREOF | CEPHALON, INC. (US) | 2015-01-08 | — | — | US | disclosed |
| WO-2014186325-A1 | PROCESSES AND INTERMEDIATES FOR PREPARING INDOLE PHARMACEUTICALS | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2014-11-20 | — | — | WO | disclosed |
| US-20100121055-A1 | PROCESSES FOR PREPARING (R)-2-METHYLPYRROLIDINE AND (S)-2-METHYLPYRROLIDINE AND TARTRATE SALTS THEREOF | CEPHALON, INC. (US) | 2010-05-13 | — | — | US | disclosed |
| US-20090176764-A1 | 2-PHENYL-1-[4-(2-AMINOETHOXY)-BENZYL]-INDOLES AS ESTROGENIC AGENTS | WYETH (US) | 2009-07-09 | — | — | US | disclosed |
| WO-2008137087-A1 | PROCESSES FOR PREPARING (R)-2-METHYLPYRROLIDINE AND (S)-2-METHYLPYRROLIDINE AND TARTRATE SALTS THEREOF | CEPHALON, INC. (US) | 2008-11-13 | — | — | WO | disclosed |
| US-7449455-B2 | 2-phenyl-1-[4-(2-aminoethoxy)-benzyl]-indoles as estrogenic agents | WYETH (US) | 2008-11-11 | — | — | US | disclosed |
| US-20080021017-A1 | 2-Phenyl-1-[4-(2-aminoethoxy)-benzyl]-indoles as estrogenic agents | WYETH (US) | 2008-01-24 | — | — | US | disclosed |
| US-7247624-B2 | 2-Phenyl-1-[4-(2-aminoethoxy)-benzyl]-indoles as estrogenic agents | WYETH (US) | 2007-07-24 | — | — | US | disclosed |
| US-20070142361-A1 | 2-Phenyl-1-[4-(2-aminoethoxy)-benzyl]-indole and estrogen formulations | WYETH (US) | 2007-06-21 | — | — | US | disclosed |
| US-20070135396-A1 | 2-Phenyl-1-[4-(2-Aminoethoxy)-Benzyl]-Indole and estrogen formulations | WYETH (US) | 2007-06-14 | — | — | US | disclosed |
| US-20070135397-A1 | 2-Phenyl-1-[4-(2-Aminoethoxy)-Benzyl]-Indole and estrogen formulations | WYETH (US) | 2007-06-14 | — | — | US | disclosed |
| US-20070054895-A1 | 2-Phenyl-1-[4-(2-aminoethoxy)-benzyl]-indoles as estrogenic agents | WYETH (US) | 2007-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150011759-A1 | PROCESSES FOR PREPARING (R)-2-METHYLPYRROLIDINE AND (S)-2-METHYLPYRROLIDINE AND TARTRATE SALTS THEREOF | TPMT, SPR, QDPR | RAB9A 2686/4885NPC1 4798/4885LTA4H 4357/4885 |
| US-20070135397-A1 | 2-Phenyl-1-[4-(2-Aminoethoxy)-Benzyl]-Indole and estrogen formulations | ESR2, ESR1, CYP19A1 | RAB9A 3487/4885NPC1 1724/4885LTA4H 1507/4885 |
| US-20070135396-A1 | 2-Phenyl-1-[4-(2-Aminoethoxy)-Benzyl]-Indole and estrogen formulations | ESR2, ESR1, CYP19A1 | RAB9A 3487/4885NPC1 1724/4885LTA4H 1507/4885 |
| US-20150374858-A1 | CONJUGATES DERIVED FROM NON-STEROIDAL ANTI-INFLAMMATORY DRUGS AND METHODS OF USE THEREOF IN IMAGING | PTGES3, PTGES, HPGDS | RAB9A 2862/4885NPC1 1730/4885LTA4H 32/4885 |
| US-11040938-B2 | Continuous flow process for the synthesis of phenylhydrazine salts and substituted phenylhydrazine salts | HPD, TYR, PDK2 | RAB9A 3335/4885NPC1 4379/4885LTA4H 4138/4885 |
| US-20100121055-A1 | PROCESSES FOR PREPARING (R)-2-METHYLPYRROLIDINE AND (S)-2-METHYLPYRROLIDINE AND TARTRATE SALTS THEREOF | TPMT, SPR, QDPR | RAB9A 2686/4885NPC1 4798/4885LTA4H 4357/4885 |
| US-20190152896-A1 | Continuous Flow Process For the Synthesis of Phenylhydrazine Salts and Substituted Phenylhydrazine Salts | HPD, TYR, PDK2 | RAB9A 3335/4885NPC1 4379/4885LTA4H 4138/4885 |
| US-20070142361-A1 | 2-Phenyl-1-[4-(2-aminoethoxy)-benzyl]-indole and estrogen formulations | ESR1, ESR2, CYP19A1 | RAB9A 3283/4885NPC1 1580/4885LTA4H 1621/4885 |
| US-20090176764-A1 | 2-PHENYL-1-[4-(2-AMINOETHOXY)-BENZYL]-INDOLES AS ESTROGENIC AGENTS | BRCA1, ESR2, PKD2 | RAB9A 4162/4885NPC1 1385/4885LTA4H 3871/4885 |
| US-20080021017-A1 | 2-Phenyl-1-[4-(2-aminoethoxy)-benzyl]-indoles as estrogenic agents | BRCA1, PKD2, CYP19A1 | RAB9A 4207/4885NPC1 1564/4885LTA4H 4257/4885 |
| US-20160107991-A1 | PROCESSES AND INTERMEDIATES FOR PREPARING INDOLE PHARMACEUTICALS | CYP19A1, IDO1, IDO2 | RAB9A 2346/4885NPC1 1771/4885LTA4H 822/4885 |
| US-20070054895-A1 | 2-Phenyl-1-[4-(2-aminoethoxy)-benzyl]-indoles as estrogenic agents | ESR2, GPER1, ESR1 | RAB9A 4109/4885NPC1 3830/4885LTA4H 2249/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.