Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 4/20 | 0.62 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.58 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | PHGDH | O43175 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MYC | P01106 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL686471 | 0.91 | SIRT1 (0.60) | SIRT1ALOX5PTGS2RAB9ANPC1 | |
| SCHEMBL9921093 | 0.91 | SIRT1 (0.63) | SIRT1ALOX5PTGS2RAB9ANPC1 | |
| SCHEMBL9921031 | 0.90 | ALOX5 (0.71) | SIRT1ALOX5PTGS2RAB9ANPC1 | |
| SCHEMBL685684 | 0.89 | KMT2A (0.57) | SIRT1ALOX5PTGS2RAB9ANPC1 | |
| SCHEMBL685015 | 0.87 | RAB9A (0.55) | SIRT1ALOX5PTGS2RAB9ANPC1 | |
| SCHEMBL683971 | 0.87 | NPC1 (0.56) | SIRT1ALOX5PTGS2RAB9ANPC1 | |
| SCHEMBL9921127 | 0.87 | SIRT1 (0.61) | SIRT1ALOX5PTGS2RAB9ANPC1 | |
| SCHEMBL686445 | 0.87 | PHGDH (0.69) | SIRT1ALOX5PTGS2RAB9ANPC1 | |
| SCHEMBL686241 | 0.84 | PHGDH (0.67) | SIRT1RAB9ANPC1MAPTPKM | |
| SCHEMBL686245 | 0.83 | ALOX5 (0.58) | SIRT1ALOX5PTGS2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120148682-A1 | FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | DOW AGROSCIENCES LLC (US) | 2012-06-14 | — | — | US | disclosed |
| US-20120010075-A1 | SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | DOW AGROSCIENCES LLC (US) | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010075-A1 | SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | SOD1, CYP51A1, SOD3 | SIRT1 2400/4885ALOX5 2022/4885PTGS2 2788/4885 |
| US-20120148682-A1 | FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | SOD1, CYP51A1, CYP4Z1 | SIRT1 1977/4885ALOX5 1904/4885PTGS2 2914/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.