Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8038051 | 0.82 | EPHX1 (0.43) | OPRM1CHRNB2CHRNA4CHRNA5CHRNA7 | |
| SCHEMBL8055435 | 0.82 | EPHX1 (0.43) | OPRM1CHRNB2CHRNA4CHRNA5CHRNA7 | |
| SCHEMBL11240147 | 0.75 | OPRM1 (0.46) | OPRM1CHRNB2CHRNA4CHRNA5CHRNA7 | |
| SCHEMBL16501770 | 0.73 | PREP (0.48) | OPRM1CHRNB4CHRNA3CHRNB2CHRNA4 | |
| SCHEMBL28645032 | 0.71 | DRD2 (0.43) | CHRNB2CHRNA4CHRNA5CHRNA7 | |
| SCHEMBL29358366 | 0.70 | CHRNB2 (0.44) | OPRM1CHRNB2CHRNA4CHRNA5CHRNA7 | |
| SCHEMBL8320704 | 0.70 | FAP (0.44) | OPRM1CHRNB2CHRNA4CHRNA5CHRNA7 | |
| SCHEMBL12506716 | 0.70 | FAP (0.44) | OPRM1CHRNB2CHRNA4CHRNA5CHRNA7 | |
| SCHEMBL8049484 | 0.70 | MTNR1A (0.47) | OPRM1CHRNB2CHRNA4CHRNA5CHRNA7 | |
| SCHEMBL19103236 | 0.70 | CYP1A2 (0.40) | OPRM1KAT2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2010185-B1 | DIHYDROTHIENOPYRIMIDINE FOR TREATING INFLAMMATORY DISORDERS | BOEHRINGER INGELHEIM INT (DE) | 2012-06-13 | — | — | EP | disclosed |