SCHEMBL992964

SCHEMBL992964

Cc1c(C)c(C)c(-c2c(C)c(C)c(C)c(C)c2O)c(O)c1C

nearest known ligand 0.39

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SENP1 Q9P0U3 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2527849 0.80 SENP1 (0.41) SENP1
SCHEMBL3132042 0.79 LDHA (0.35) SENP1
SCHEMBL397768 0.79 ALOX5 (0.36) SENP1
SCHEMBL31061824 0.79 ALDH1A1 (0.41)
SCHEMBL158803 0.79 ALDH1A1 (0.41)
SCHEMBL2219446 0.75 IGF1R (0.33) SENP1
Hydrochloric Acid SCHEMBL28468873 0.75 ALOX5 (0.35) SENP1
SCHEMBL70689 0.75 ALOX5 (0.35) SENP1
SCHEMBL1552332 0.75 TRPA1 (0.38) SENP1
Durohydroquinone SCHEMBL69786 0.74 ALOX5 (0.38) SENP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1467958-B1 PROCESS FOR PREPARING 3,3',5,5',6,6'-HEXAALKYL-2,2'-BIPHENOLS, 3,3',4,4',5,5'-HEXAALKYL-2,2'-BIPHENOLS AND 3,3',4,4',5,5',6,6'-OCTAALKYL-2,2'-BIPHENOLS INVISTA TECH SARL (CH) 2014-01-08 EP disclosed
US-20130090438-A1 PROCESS FOR PRODUCING HIGH MOLECULAR WEIGHT POLYETHYLENE TICONA GMBH (DE) 2013-04-11 US disclosed
US-20130090400-A1 PROCESS FOR PRODUCING HIGH MOLECULAR WEIGHT POLYETHYLENE TICONA GMBH (DE) 2013-04-11 US disclosed
EP-1905511-B1 Polymeric phosphorus-containing compositions and their use in hydrocyanation, unsaturated nitrile isomerization and hydroformylation reactions INVISTA TECH SARL (CH) 2013-03-27 EP disclosed
US-8084611-B2 Process for preparing tetrahydroquinoline derivatives MITSUBISHI TANABE PHARMA CORPORATION (JP) 2011-12-27 US disclosed
EP-2279993-A1 Process for preparing 3,3',5,5',6,6'-hexaalkyl-2,2'-biphenols, 3,3',4,4',5,5'-hexaalkyl-2,2'-biphenols and 3,3',4,4',5,5',6,6'-octaalkyl-2,2'-biphenols INVISTA Technologies S.à.r.l. (CH) 2011-02-02 EP disclosed
EP-2277623-A2 Polymeric phosphorus-containing compositions and their use in hydrocyanation, unsaturated nitrile isomerization and hydroformylation reactions INVISTA Technologies S.à.r.l. (CH) 2011-01-26 EP disclosed
US-20090292125-A1 PROCESS FOR PREPARING TETRAHYDROQUINOLINE DERIVATIVES MITSUBISHI TANABE PHARMA CORPORATION (JP) 2009-11-26 US disclosed
EP-1905511-A2 Phosphorus-containing compositions and their use in hydrocyanation, isomerization and hydroformylation reactions INVISTA Technologies S.à.r.l. (CH) 2008-04-02 EP disclosed
US-6924345-B2 Phosphorus-containing compositions and their use in hydrocyanation, isomerization and hydroformylation reactions INVISTA NORTH AMERICA S.A R.L. (US) 2005-08-02 US disclosed
US-20040054105-A1 Phosphorus-containing compositions and their use in hydrocyanation, isomerization and hydroformylation reactions INV NYLON CHEMICALS AMERICAS, LLC 2004-03-18 US disclosed
US-6660876-B2 Ethylenically unsaturated, phosphorus-containing, bidentate ligands E. I. DU PONT DE NEMOURS AND COMPANY 2003-12-09 US disclosed
US-20030144440-A1 Phosphorus-containing compositions and their use in hydrocyanation, isomerization and hydroformylation reactions INV NYLON CHEMICALS AMERICAS, LLC 2003-07-31 US disclosed
US-20030100802-A1 Process for preparing 3,3',5,5',6,6'-hexaalkyl-2,2'-biphenols,3,3',4,4',5,5'-hexaalkyl-2,2'-biphenols and 3,3',4,4',5,5',6,6'-octaalkyl-2,2'-biphenols SHAPIRO RAFAEL (US) 2003-05-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090292125-A1 PROCESS FOR PREPARING TETRAHYDROQUINOLINE DERIVATIVES PCSK9, LSS, DHCR7 SENP1 1592/4885
US-20030100802-A1 Process for preparing 3,3',5,5',6,6'-hexaalkyl-2,2'-biphenols,3,3',4,4',5,5'-hexaalkyl-2,2'-biphenols and 3,3',4,4',5,5',6,6'-octaalkyl-2,2'-biphenols CYP4B1, UGT1A4, CYP4X1 SENP1 4060/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.