Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3GNRHRMPLPDE3APDE3BPDE4APDE4BPDE4CPDE4DPPARASLC5A2
The experimentally established mechanism targets of Choline. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.60 |
| ▸ | CHRM2 | P08172 | 7/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 7/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 7/20 | 0.39 |
| ▸ | GALR3 | O60755 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Choline SCHEMBL338525 | 0.97 | MEN1 (0.63) | MEN1LMNAKMT2ACYP3A4SLC5A7 | |
| Choline SCHEMBL993189 | 0.95 | LMNA (0.60) | MEN1LMNAKMT2ACYP3A4SLC5A7 | |
| Choline SCHEMBL992915 | 0.86 | MEN1 (0.71) | MEN1LMNAKMT2ACYP3A4SLC5A7 | |
| Choline SCHEMBL29118960 | 0.83 | MEN1 (0.77) | MEN1LMNAKMT2ACYP3A4SLC5A7 | |
| Choline SCHEMBL21800980 | 0.83 | CYP3A4 (0.77) | MEN1LMNAKMT2ACYP3A4SLC5A7 | |
| Choline SCHEMBL2469440 | 0.83 | MEN1 (0.67) | MEN1LMNAKMT2ACYP3A4SLC5A7 | |
| Choline SCHEMBL31315413 | 0.83 | — | — | |
| Choline SCHEMBL143291 | 0.83 | MEN1 (0.86) | MEN1LMNAKMT2ACYP3A4SLC5A7 | |
| Choline SCHEMBL54947 | 0.83 | — | — | |
| Choline SCHEMBL30589345 | 0.83 | MEN1 (0.86) | MEN1LMNAKMT2ACYP3A4SLC5A7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250360691-A1 | RELEASE FILM AND LAMINATE | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2025-11-27 | — | — | US | disclosed |
| CN-117866376-A | Polyacetal resin composition | 旭化成株式会社 | 2024-04-12 | — | — | CN | disclosed |
| EP-3354688-B1 | POLYACETAL RESIN COMPOSITION AND MOLDED BODY THEREOF | ASAHI CHEMICAL IND (JP) | 2024-03-13 | — | — | EP | disclosed |
| EP-4032944-B1 | METHOD FOR PRODUCING OXYMETHYLENE COPOLYMER RESIN COMPOSITION, AND OXYMETHYLENE COPOLYMER RESIN COMPOSITION | MITSUBISHI GAS CHEMICAL CO (JP) | 2023-12-13 | — | — | EP | disclosed |
| US-11820857-B2 | Method for producing oxymethylene copolymer resin composition, and oxymethylene copolymer resin composition | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2023-11-21 | — | — | US | disclosed |
| US-20220356290-A1 | METHOD FOR PRODUCING OXYMETHYLENE COPOLYMER RESIN COMPOSITION, AND OXYMETHYLENE COPOLYMER RESIN COMPOSITION | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2022-11-10 | — | — | US | disclosed |
| CN-114402028-B | Method for producing oxymethylene copolymer resin composition, and oxymethylene copolymer resin composition | 三菱瓦斯化学株式会社 | 2022-08-30 | — | — | CN | disclosed |
| EP-4032944-A1 | METHOD FOR PRODUCING OXYMETHYLENE COPOLYMER RESIN COMPOSITION, AND OXYMETHYLENE COPOLYMER RESIN COMPOSITION | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2022-07-27 | — | — | EP | disclosed |
| CN-114402028-A | Method for producing oxymethylene copolymer resin composition, and oxymethylene copolymer resin composition | 三菱瓦斯化学株式会社 | 2022-04-26 | — | — | CN | disclosed |
| CN-108026352-B | Polyacetal resin composition and molded article thereof | 旭化成株式会社 | 2020-07-03 | — | — | CN | disclosed |
| US-20110015321-A1 | POLYACETAL RESIN COMPOSITION AND PREPARATION PROCESS THEREOF | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2011-01-20 | — | — | US | disclosed |
| EP-2267075-A1 | POLYACETAL RESIN COMPOSITION AND METHOD FOR PRODUCING THE SAME | Asahi Kasei Chemicals Corporation (JP) | 2010-12-29 | — | — | EP | disclosed |
| US-7772310-B2 | Polyacetal resin composition | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2010-08-10 | — | — | US | disclosed |
| US-7638569-B2 | Gear | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2009-12-29 | — | — | US | disclosed |
| US-20090318600-A1 | POLYACETAL RESIN COMPOSITION | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2009-12-24 | — | — | US | disclosed |
| US-7625969-B2 | Polyacetal resin composition | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2009-12-01 | — | — | US | disclosed |
| EP-1908991-B1 | GEAR | ASAHI KASEI CHEMICALS CORP (JP) | 2009-09-30 | — | — | EP | disclosed |
| US-20090137712-A1 | ORAL WASH | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2009-05-28 | — | — | US | disclosed |
| EP-1908991-A1 | GEAR | Asahi Kasei Chemicals Corporation (JP) | 2008-04-09 | — | — | EP | disclosed |
| US-20070179231-A1 | Polyacetal resin composition | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2007-08-02 | — | — | US | disclosed |